Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H20N4O.C7H8O3S.H2O |
| Molecular Weight | 510.605 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.CC1=CC=C(C=C1)S(O)(=O)=O.NC(=O)C2=CC=CC3=CN(N=C23)C4=CC=C(C=C4)[C@@H]5CCCNC5
InChI
InChIKey=ACNPUCQQZDAPJH-FMOMHUKBSA-N
InChI=1S/C19H20N4O.C7H8O3S.H2O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;1-6-2-4-7(5-3-6)11(8,9)10;/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);2-5H,1H3,(H,8,9,10);1H2/t14-;;/m1../s1
Approval Year
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C62554
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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EU/3/10/760(POSITIVE)
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | On 4 August 2010, orphan designation (EU/3/10/760) was granted by the European Commission to Merck Sharp & Dohme Limited, United Kingdom, for (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl] phenyl} piperidine tosylate monohydrate salt (also known as MK-4827) for the treatment of ovarian cancer. The sponsorship was transferred to Tesaro U.K. Limited, United Kingdom, in December 2012. | ||
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195Q483UZD
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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1613220-15-7
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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SUB183938
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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100000170106
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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74763937
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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m11995
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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DBSALT002590
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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C133238
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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176844
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | |||
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EU/3/10/787(POSITIVE)
Created by
admin on Sat Dec 16 09:12:11 UTC 2023 , Edited by admin on Sat Dec 16 09:12:11 UTC 2023
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PRIMARY | On 1 October 2010, orphan designation (EU/3/10/787) was granted by the European Commission to Merck Sharp & Dohme Limited, United Kingdom, for (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl] phenyl} piperidine tosylate monohydrate salt for the treatment of mantle-cell lymphoma. The sponsorship was transferred to Tesaro U.K. Limited, United Kingdom, in December 2012. |
ACTIVE MOIETY
SUBSTANCE RECORD
