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Details

Stereochemistry RACEMIC
Molecular Formula C26H25ClN2O3
Molecular Weight 448.941
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TOLVAPTAN

SMILES

CC1=CC=CC=C1C(=O)NC2=CC(C)=C(C=C2)C(=O)N3CCCC(O)C4=C3C=CC(Cl)=C4

InChI

InChIKey=GYHCTFXIZSNGJT-UHFFFAOYSA-N
InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
TOLVAPTAN
DASH   EMA EPAR   INN   JAN   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
INN   USAN  
Official Name English
TOLVAPTAN [ORANGE BOOK]
Common Name English
OPC-41061
Code English
TOLVAPTAN [MART.]
Common Name English
JINARC
Brand Name English
SAMSCA
Brand Name English
JYNARQUE
Brand Name English
tolvaptan [INN]
Common Name English
(±)-4'-((7-CHLORO-2,3,4,5-TETRAHYDRO-5-HYDROXY-1H-1-BENZAZEPIN-1-YL) CARBONYL)-O-TOLU-M-TOLUIDIDE
Common Name English
OPC-41061(TOLVAPTAN)
Code English
TOLVAPTAN [EMA EPAR]
Common Name English
BENZAMIDE, N-(4-((7-CHLORO-2,3,4,5-TETRAHYDRO-5-HYDROXY-1H-1-BENZAZEPIN-1-YL)CARBONYL)-3-METHYLPHENYL)-2-METHYL-
Systematic Name English
TOLVAPTAN [MI]
Common Name English
TOLVAPTAN [VANDF]
Common Name English
TOLVAPTAN [JAN]
Common Name English
Tolvaptan [WHO-DD]
Common Name English
TOLVAPTAN [USAN]
Common Name English
Classification Tree Code System Code
LIVERTOX NBK548503
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
WHO-ATC C03XA01
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
EMA ASSESSMENT REPORTS SAMSCA (AUTHORIZED: INAPPROPRIATE ADH SYNDROME)
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
WHO-VATC QC03XA01
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
EMA ASSESSMENT REPORTS JINARC (AUTHORIZED: POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT)
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
FDA ORPHAN DRUG 347311
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
NDF-RT N0000193181
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
NCI_THESAURUS C2180
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
EU-Orphan Drug EU/3/13/1175
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
Code System Code Type Description
USAN
LL-16
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
EVMPD
SUB22755
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
SMS_ID
100000091683
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
DRUG BANK
DB06212
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
ChEMBL
CHEMBL344159
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
DAILYMED
21G72T1950
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
WIKIPEDIA
Tolvaptan
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
DRUG CENTRAL
4110
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
CAS
150683-30-0
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
EPA CompTox
DTXSID3048780
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
NCI_THESAURUS
C77082
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
MERCK INDEX
m10969
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY Merck Index
HSDB
8196
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
INN
7969
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
FDA UNII
21G72T1950
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
RXCUI
358257
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY RxNorm
PUBCHEM
216237
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
IUPHAR
2226
Created by admin on Fri Dec 15 15:26:46 UTC 2023 , Edited by admin on Fri Dec 15 15:26:46 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of TOLVAPTAN
METABOLITE (PARENT)
Structure of DM-4132
METABOLITE (PARENT)
Structure of DM-4130
METABOLITE (PARENT)
Structure of DM-4128
METABOLITE (PARENT)
Structure of DM-4129
METABOLITE (PARENT)
Structure of DM-4111
METABOLITE (PARENT)
Structure of DM-4105
METABOLITE (PARENT)
Structure of DM-4110
METABOLITE (PARENT)
Structure of DM-4131
METABOLITE (PARENT)
Structure of DM-4119
METABOLITE (PARENT)
Structure of DM-4104
METABOLITE (PARENT)
Structure of DM-4133
METABOLITE INACTIVE (PARENT)
Structure of DM-4107
SALT/SOLVATE (PARENT)
Structure of TOLVAPTAN PHOSPHATE SODIUM
NIH
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