BOSUTINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H29Cl2N5O3
Molecular Weight	530.446
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BOSUTINIB

Structure Search

SMILES

COC1=C(Cl)C=C(Cl)C(NC2=C(C=NC3=CC(OCCCN4CCN(C)CC4)=C(OC)C=C23)C#N)=C1

InChI

InChIKey=UBPYILGKFZZVDX-UHFFFAOYSA-N

InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)

HIDE SMILES / InChI

Approval Year

Name

Type

Language

BOSUTINIB

Official Name

English

BOSUTINIB [USAN]

Common Name

English

BOSULIF

Common Name

English

BOSUTINIB [MI]

Common Name

English

SK-606

Code

English

BOSUTINIB [MART.]

Common Name

English

3-QUINOLINECARBONITRILE, 4-((2,4-DICHLORO-5-METHOXYPHENYL)AMINO)-6-METHYL-1-PIPERAZINYL)PROPOXY)-

Common Name

English

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile

Systematic Name

English

BOSUTINIB [VANDF]

Common Name

English

SKI-606

Code

English

bosutinib [INN]

Common Name

English

Bosutinib [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

L01XE14

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

FDA ORPHAN DRUG

274808

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

EU-Orphan Drug

EU/3/10/762

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

NDF-RT

N0000175605

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

LIVERTOX

NBK547951

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

WHO-VATC

QL01XE14

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

NCI_THESAURUS

C155700

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

Code System Code Type Description

NDF-RT

N0000185503

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

P-Glycoprotein Inhibitors [MoA]

MESH

C471992

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

CHEBI

39112

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

IUPHAR

5710

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

ChEMBL

CHEMBL288441

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

MERCK INDEX

m2627

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

Merck Index

DRUG BANK

DB06616

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

SMS_ID

100000090716

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

USAN

RR-46

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

LACTMED

Bosutinib

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

EVMPD

SUB29176

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

FDA UNII

5018V4AEZ0

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

EPA CompTox

DTXSID10861568

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

RXCUI

1307619

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

RxNorm

INN

8715

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

PUBCHEM

5328940

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

DAILYMED

5018V4AEZ0

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

CHEBI

68533

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

WIKIPEDIA

BOSUTINIB

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

NCI_THESAURUS

C60809

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

DRUG CENTRAL

4359

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

CAS

380843-75-4

Created by admin on Fri Dec 15 17:20:56 UTC 2023 , Edited by admin on Fri Dec 15 17:20:56 UTC 2023

PRIMARY

ACTIVE MOIETY


					5018V4AEZ0

BOSUTINIB

METABOLITE INACTIVE (PARENT)


					94F331LB1W

OXYDECHLORINATED BOSUTINIB HYDROGEN SULFATE

PARENT (METABOLITE INACTIVE)


					ESC667086F

OXYDECHLORINATED BOSUTINIB

PARENT (METABOLITE INACTIVE)


					8870T6W3VG

N-DESMETHYL BOSUTINIB

SALT/SOLVATE (PARENT)


					8897ZFQ8MU

BOSUTINIB DIHYDRATE

SALT/SOLVATE (PARENT)


					844ZJE6I55

BOSUTINIB MONOHYDRATE

SALT/SOLVATE (PARENT)


					EZM4KL4P89

Bosutinib methanoate