TAK-733

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H15F2IN4O4
Molecular Weight	504.2267
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TAK-733

Structure Search

SMILES

CN1C(=O)C(F)=C(NC2=CC=C(I)C=C2F)C3=C1N=CN(C[C@@H](O)CO)C3=O

InChI

InChIKey=RCLQNICOARASSR-SECBINFHSA-N

InChI=1S/C17H15F2IN4O4/c1-23-15-12(16(27)24(7-21-15)5-9(26)6-25)14(13(19)17(23)28)22-11-3-2-8(20)4-10(11)18/h2-4,7,9,22,25-26H,5-6H2,1H3/t9-/m1/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

TAK-733

Code

English

MEK INHIBITOR TAK-733

Common Name

English

TAK 733 [WHO-DD]

Common Name

English

3-[(2R)-2,3-Dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione

Systematic Name

English

REC-4881

Code

English

(R)-3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLUORO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO(2,3-D)PYRIMIDINE-4,7(3H,8H)-DIONE

Systematic Name

English

TAK733

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C69145

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

FDA ORPHAN DRUG

817621

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

NCI_THESAURUS

C129825

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID20648089

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

ChEMBL

CHEMBL1615025

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

PUBCHEM

24963252

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

FDA UNII

5J61HSP0QJ

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

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DRUG BANK

DB12241

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

SMS_ID

300000041469

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

CAS

1035555-63-5

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

NCI_THESAURUS

C84858

Created by admin on Sat Dec 16 08:35:37 UTC 2023 , Edited by admin on Sat Dec 16 08:35:37 UTC 2023

PRIMARY

ACTIVE MOIETY


					5J61HSP0QJ

TAK-733