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Details

Stereochemistry RACEMIC
Molecular Formula C17H16F6N2O.ClH
Molecular Weight 414.773
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEFLOQUINE HYDROCHLORIDE

SMILES

Cl.[H][C@@]1(CCCCN1)[C@@H](O)C2=C3C=CC=C(C3=NC(=C2)C(F)(F)F)C(F)(F)F

InChI

InChIKey=WESWYMRNZNDGBX-YLCXCWDSSA-N
InChI=1S/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H/t12-,15+;/m1./s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
MEFLOQUINE HYDROCHLORIDE
EP   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN  
Official Name English
MEFLOQUINE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
MEFLOQUINE HYDROCHLORIDE [MART.]
Common Name English
RO-215998001
Code English
MEFLOQUINE HYDROCHLORIDE [WHO-IP]
Common Name English
MEFLOQUINI HYDROCHLORIDUM [WHO-IP LATIN]
Common Name English
NSC-157387
Code English
MEFLOQUINE HCL
Common Name English
MEFLOQUINE HYDROCHLORIDE [USP-RS]
Common Name English
4-QUINOLINEMETHANOL, .ALPHA.-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, MONOHYDROCHLORIDE, (R*,S*)- (±)-
Common Name English
DL-ERYTHRO-.ALPHA.-2-PIPERIDYL-2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINEMETHANOL MONOHYDROCHLORIDE
Common Name English
MEFLOQUINE HYDROCHLORIDE [VANDF]
Common Name English
RO-21-5998/001
Code English
MEFLOQUINE HYDROCHLORIDE [EP MONOGRAPH]
Common Name English
Mefloquine hydrochloride [WHO-DD]
Common Name English
RO-21-5998
Code English
WR-142490
Code English
LORIAM
Brand Name English
LARIAM
Brand Name English
MEFLOQUINE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
MEFLOQUINE HYDROCHLORIDE [EP IMPURITY]
Common Name English
MEFLOQUINE HYDROCHLORIDE [USAN]
Common Name English
MEFLOQUINE HYDROCHLORIDE [JAN]
Common Name English
RO 21-5998/001
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 18687
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
NCI_THESAURUS C271
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
FDA ORPHAN DRUG 26287
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
Code System Code Type Description
USAN
W-48
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
DRUG BANK
DBSALT000311
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
CAS
51773-92-3
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
EVMPD
SUB14492MIG
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
PUBCHEM
65329
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
NSC
157387
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
EPA CompTox
DTXSID1047819
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
NCI_THESAURUS
C47600
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
ChEMBL
CHEMBL416956
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
SMS_ID
100000076533
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
DAILYMED
5Y9L3636O3
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
FDA UNII
5Y9L3636O3
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
RS_ITEM_NUM
1379059
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
RXCUI
82130
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
257-412-0
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY
MERCK INDEX
m7142
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY Merck Index
WHO INTERNATIONAL PHARMACOPEIA
MEFLOQUINE HYDROCHLORIDE
Created by admin on Fri Dec 15 15:24:53 UTC 2023 , Edited by admin on Fri Dec 15 15:24:53 UTC 2023
PRIMARY Description: A white to slightly yellow, crystalline powder. Solubility: Very slightly soluble in water; freely soluble in methanol R; soluble in ethanol (~750 g/L) TS; sparingly soluble in dichloromethane R. Category: Antimalarial. Storage: Mefloquine hydrochloride should be kept in a tightly closed container, protected from light. Additional information: Mefloquine hydrochloride may exhibit polymorphism. It melts at about 260 ?C, with decomposition. Requirement: Mefloquine hydrochloride contains not less than 99.0% and not more than 101.0% of C17H16F6N2O,HCl, calculated with reference to the anhydrous substance.
ACTIVE MOIETY
Structure of MEFLOQUINE
NIH
NCATS
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