PEXIDARTINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H15ClF3N5
Molecular Weight	417.815
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PEXIDARTINIB

Structure Search

SMILES

FC(F)(F)C1=NC=C(CNC2=NC=C(CC3=CNC4=C3C=C(Cl)C=N4)C=C2)C=C1

InChI

InChIKey=JGWRKYUXBBNENE-UHFFFAOYSA-N

InChI=1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29)

HIDE SMILES / InChI

Approval Year

Name

Type

Language

PEXIDARTINIB

Official Name

English

pexidartinib [INN]

Common Name

English

PLX3397

Code

English

Pexidartinib [WHO-DD]

Common Name

English

PLX-3397

Code

English

PEXIDARTINIB [USAN]

Common Name

English

PEXIDARTINIB [MI]

Common Name

English

CML-261

Code

English

5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine

Systematic Name

English

3-PYRIDINEMETHANAMINE, N-(5-((5-CHLORO-1H-PYRROLO(2,3-B)PYRIDIN-3-YL)METHYL)-2-PYRIDINYL)-6-(TRIFLUOROMETHYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

NCI_THESAURUS

C1967

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

Code System Code Type Description

CHEBI

145373

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

ChEMBL

CHEMBL3545158

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

CAS

1029044-16-3

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

SMS_ID

100000171886

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

DAILYMED

6783M2LV5X

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

INN

10056

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

DRUG BANK

DB12978

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

USAN

EF-89

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

PUBCHEM

25151352

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

LACTMED

Pexidartinib

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

MERCK INDEX

m12153

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

WIKIPEDIA

Pexidartinib

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

NCI_THESAURUS

C88303

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

RXCUI

2183102

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

CAS

1447274-99-8

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

NO STRUCTURE GIVEN

DRUG CENTRAL

5343

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

FDA UNII

6783M2LV5X

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

EPA CompTox

DTXSID301026482

Created by admin on Fri Dec 15 16:01:22 UTC 2023 , Edited by admin on Fri Dec 15 16:01:22 UTC 2023

PRIMARY

ACTIVE MOIETY


					6783M2LV5X

SALT/SOLVATE (PARENT)


					YS6WAI3XN7

PEXIDARTINIB HYDROCHLORIDE