U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C29H33ClN2O2
Molecular Weight 477.038
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LOPERAMIDE

SMILES

CN(C)C(=O)C(CCN1CCC(O)(CC1)C2=CC=C(Cl)C=C2)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=RDOIQAHITMMDAJ-UHFFFAOYSA-N
InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
LOPERAMIDE
INN   MI   VANDF   WHO-DD  
INN  
Official Name English
LOPERAMIDE [VANDF]
Common Name English
1-PIPERIDINEBUTANAMIDE, 4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-.ALPHA.,.ALPHA.-DIPHENYL-
Systematic Name English
Loperamide [WHO-DD]
Common Name English
4-(P-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-.ALPHA.,.ALPHA.-DIPHENYL-1-PIPERIDINEBUTYRAMIDE
Common Name English
loperamide [INN]
Common Name English
LOPERAMIDE [MI]
Common Name English
LOPERAMIDE [JAN]
Common Name English
LOPERAMIDE OXIDE MONOHYDRATE IMPURITY A [EP IMPURITY]
Common Name English
Classification Tree Code System Code
WHO-VATC QA07DA03
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
WHO-ATC A07DA53
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
WHO-ATC A07DA03
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
NCI_THESAURUS C1506
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
NDF-RT N0000175690
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
NCI_THESAURUS C266
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
NDF-RT N0000000174
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
LIVERTOX NBK547935
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
WHO-VATC QA07DA53
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
Code System Code Type Description
FDA UNII
6X9OC3H4II
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
CAS
53179-11-6
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
INN
3098
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
EPA CompTox
DTXSID6045165
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
ChEMBL
CHEMBL841
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
PUBCHEM
3955
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
MESH
D008139
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
WIKIPEDIA
LOPERAMIDE
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
HSDB
8344
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
NCI_THESAURUS
C618
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
LACTMED
Loperamide
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
EVMPD
SUB08572MIG
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
SMS_ID
100000082007
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
IUPHAR
7215
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
CHEBI
6532
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
DRUG CENTRAL
1599
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
DRUG BANK
DB00836
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
RXCUI
6468
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY RxNorm
MERCK INDEX
m6898
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
258-416-5
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
DAILYMED
6X9OC3H4II
Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of LOPERAMIDE
METABOLITE ACTIVE (PARENT)
Structure of DESMETHYLLOPERAMIDE
PRODRUG (METABOLITE ACTIVE)
Structure of LOPERAMIDE OXIDE
SALT/SOLVATE (PARENT)
Structure of LOPERAMIDE HYDROCHLORIDE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966