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Details

Stereochemistry ACHIRAL
Molecular Formula C23H27FN4O2
Molecular Weight 410.4845
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of FAMITINIB

SMILES

CCN(CC)CCN1CCC2=C(C(C)=C(N2)\C=C3/C(=O)NC4=C3C=C(F)C=C4)C1=O

InChI

InChIKey=GKEYKDOLBLYGRB-LGMDPLHJSA-N
InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
FAMITINIB
INN  
Official Name English
(Z)-5-(2-(DIETHYLAMINO)ETHYL)-2-((5-FLUORO-2-OXOINDOLIN-3-YLIDENE)METHYL)-3-METHYL-6,7-DIHYDRO-1H-PYRROLO(3,2-C)PYRIDIN-4(5H)-ONE
Systematic Name English
Famitinib [WHO-DD]
Common Name English
4H-PYRROLO(3,2-C)PYRIDIN-4-ONE, 5-(2-(DIETHYLAMINO)ETHYL)-2-((Z)-(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL)-1,5,6,7-TETRAHYDRO-3-METHYL-
Systematic Name English
4H-PYRROLO(3,2-C)PYRIDIN-4-ONE, 5-(2-(DIETHYLAMINO)ETHYL)-2-((5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL)-1,5,6,7-TETRAHYDRO-3-METHYL-
Systematic Name English
famitinib [INN]
Common Name English
SHR1020
Code English
SHR-1020
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129825
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
NCI_THESAURUS C1967
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
Code System Code Type Description
NCI_THESAURUS
C97512
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
CAS
1044040-56-3
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
SMS_ID
100000169823
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
ChEMBL
CHEMBL3545026
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
INN
11724
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
EVMPD
SUB183614
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
PUBCHEM
16662431
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
CAS
945380-27-8
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
NON-SPECIFIC STEREOCHEMISTRY
FDA UNII
768FW21J3L
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
DRUG BANK
DB11741
Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of FAMITINIB
METABOLITE ACTIVE (PARENT)
Structure of SHR-116837
SALT/SOLVATE (PARENT)
Structure of FAMITINIB L-MALATE
NIH
NCATS
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