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Details

Stereochemistry ABSOLUTE
Molecular Formula C36H47N5O4.H2O4S
Molecular Weight 711.868
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of INDINAVIR SULFATE

SMILES

OS(O)(=O)=O.CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H]4[C@H](O)CC5=C4C=CC=C5

InChI

InChIKey=NUBQKPWHXMGDLP-BDEHJDMKSA-N
InChI=1S/C36H47N5O4.H2O4S/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43;1-5(2,3)4/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45);(H2,1,2,3,4)/t28-,29+,31+,32-,33+;/m1./s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
INDINAVIR SULFATE
HSDB   MART.   MI   ORANGE BOOK   USAN   USP   VANDF   WHO-DD   WHO-IP  
USAN  
Official Name English
CRIXIVAN
Brand Name English
L-735524
Code English
INDINAVIR SULFATE [WHO-IP]
Common Name English
INDINAVIR SULFATE [VANDF]
Common Name English
INDINAVIR SULFATE [MI]
Common Name English
D-ERYTHRO-PENTONAMIDE, 2,3,5-TRIDEOXY-N-(2,3-DIHYDRO-2-HYDROXY-1H-INDEN-1-YL)-5-(2-(((1,1-DIMETHYLETHYL)AMINO)CARBONYL)-4-(3-PYRIDINYLMETHYL)-1-PIPERAZINYL)-2-(PHENYLMETHYL)-, (1(1S,2R,5(S))-, SULFATE (1:1) (SALT)
Common Name English
INDINAVIR SULPHATE [EMA EPAR]
Common Name English
Indinavir sulfate [WHO-DD]
Common Name English
NSC-697197
Code English
MK-639
Code English
INDINAVIRI SULFAS [WHO-IP LATIN]
Common Name English
(.ALPHA.R,.GAMMA.S,2S)-.ALPHA.-BENZYL-2-(TERT-BUTYLCARBAMOYL)-.GAMMA.-HYDROXY-N-((1S,2R)-2-HYDROXY-1-INDANYL)-4-(3-PYRIDYLMETHYL)-1-PIPERAZINEVALERAMIDE SULPHATE (1:1) (SALT)
Common Name English
D-ERYTHRO-PENTONAMIDE, 2,3,5-TRIDEOXY-N-(2,3-DIHYDRO-2-HYDROXY-1H-INDEN-1-YL)-5-(2-(((1,1-DIMETHYLETHYL)AMINO)CARBONYL)-4-(3-PYRIDINYLMETHYL)-1-PIPERAZINYL)-2-(PHENYLMETHYL)-, (1(1S,2R,5(S))-, SULPHATE (1:1) (SALT)
Common Name English
L-735,524
Code English
INDINAVIR SULFATE [USAN]
Common Name English
INDINAVIR SULFATE [MART.]
Common Name English
(αR,γS,2S)-α-Benzyl-2-(tert-butylcarbamoyl)-γ-hydroxy-N-[(1S,2R)-2-hydroxy-1-indanyl]-4-(3-pyridylmethyl)-1-piperazinevaleramide sulfate (1:1) (salt)
Common Name English
INDINAVIR SULFATE [ORANGE BOOK]
Common Name English
INDINAVIR SULPHATE
EMA EPAR  
Common Name English
INDINAVIR SULFATE [HSDB]
Common Name English
INDINAVIR SULFATE [USP MONOGRAPH]
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS CRIXIVAN (AUTHORIZED: HIV INFECTIONS)
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
NCI_THESAURUS C97366
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
Code System Code Type Description
PUBCHEM
5462355
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
CAS
157810-81-6
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
FDA UNII
771H53976Q
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
SMS_ID
100000086983
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
EPA CompTox
DTXSID1044221
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
HSDB
7158
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
NCI_THESAURUS
C1662
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
NSC
697197
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
DRUG BANK
DBSALT000338
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
DAILYMED
771H53976Q
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
USAN
HH-15
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
ChEMBL
CHEMBL115
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
INDINAVIR SULFATE
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY Description: A white or almost white powder. Solubility: Freely soluble in water, soluble in methanol. Category: Antiretroviral (protease inhibitor). Storage: Indinavir sulfate should be kept in a tightly closed container, protected from light.Additional information: Indinavir sulfate occurs as the monoethanolate which is hygroscopic. It converts to the hydrate upon loss of ethanol and exposure to moist air. Definition: Indinavir sulfate contains not less than 98.5% and not more than 101.0% of (C36H47N5O4,H2O4S), calculated with reference to the anhydrous and ethanol free substance.
MERCK INDEX
m6253
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY Merck Index
RXCUI
203153
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY RxNorm
EVMPD
SUB02666MIG
Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023
PRIMARY
SUBSTANCE RECORD
Structure of INDINAVIR SULFATE
NIH
NCATS
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