U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C47H73NO17
Molecular Weight 924.079
Optical Activity UNSPECIFIED
Defined Stereocenters 19 / 19
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Amphotericin B

SMILES

[H][C@]12C[C@@H](O[C@]3([H])O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2

InChI

InChIKey=APKFDSVGJQXUKY-INPOYWNPSA-N
InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
Amphotericin B
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN  
Official Name English
AMPHOTERICIN
Common Name English
AMPHOTEC
Brand Name English
AMPHOTERICIN B LIPOSOME [VANDF]
Common Name English
Amphotericin b [WHO-DD]
Common Name English
Amphotericin b, liposome [WHO-DD]
Common Name English
AMBISOME
Brand Name English
AMPHOTERICIN B LIPID COMPLEX [MI]
Common Name English
AMPHO-MORONAL
Brand Name English
AMBIL
Brand Name English
FUNGILIN
Brand Name English
AMPHOTERICIN B LIPOSOME
VANDF  
Common Name English
AMPHOTERICIN B [VANDF]
Common Name English
ABELCET, LIPOSOMAL AMPHOTERICIN B
Common Name English
AMPHOTERICIN B [USP MONOGRAPH]
Common Name English
ABELCET
Common Name English
AMPHOTERICIN B [ORANGE BOOK]
Common Name English
ABLC
Common Name English
AMPHOTERICIN B [MART.]
Common Name English
AMPHOTERICIN B LIPOSOMAL
Common Name English
amphotericin b [INN]
Common Name English
AMPHOTERICIN B [EP MONOGRAPH]
Common Name English
FUNGIZONE
Brand Name English
AMPHOTOCERIN
Common Name English
AMPHOTERICIN B LIPOSOMAL COMPLEX [MI]
Common Name English
AMPHOTERICIN B [JAN]
Common Name English
AMPHOTERICIN B LIPID COMPLEX
MI   VANDF  
Common Name English
AMPHOTERICIN B [WHO-IP]
Common Name English
AMPHOTERICIN B [MI]
Common Name English
AMPHOTERICIN B LIPOSOMAL COMPLEX
MI  
Common Name English
NSC-527017
Code English
AMPHOTERICIN B [HSDB]
Common Name English
AMPHOTERICIN B LIPID COMPLEX [VANDF]
Common Name English
HALIZON
Common Name English
AMPHOTERICINUM B [WHO-IP LATIN]
Common Name English
AMPHOTERICIN B [USP-RS]
Common Name English
Classification Tree Code System Code
WHO-VATC QJ02AA01
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
NDF-RT N0000175498
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 315310
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.5.2
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-ATC G01AA03
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 416113
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-VATC QG01AA03
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
NDF-RT N0000175510
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-ATC J02AA01
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 99496
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-VATC QA07AA07
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 210805
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 57891
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-ATC A07AA07
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 99696
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 97796
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-ATC A01AB04
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 97396
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-VATC QA01AB04
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 97696
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 97096
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.3
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 96996
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
NCI_THESAURUS C514
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 703119
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
NDF-RT N0000007672
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
FDA ORPHAN DRUG 99596
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
LIVERTOX NBK548141
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
Code System Code Type Description
RXCUI
236594
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
ALTERNATIVE
RXCUI
2001759
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
ALTERNATIVE
ECHA (EC/EINECS)
215-742-2
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
NSC
527017
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
DRUG CENTRAL
197
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
WIKIPEDIA
AMPHOTERICIN B
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
RXCUI
732
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
AMPHOTERICIN B
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY Description: A yellow to orange powder; odourless or almost odourless. Solubility: Practically insoluble in water, ethanol (~750 g/l) TS, toluene R and ether R; soluble in 200 parts of dimethylformamide R and in 20 parts of dimethyl sulfoxide R, slightly soluble in methanol R. Category: Antifungal drug. Storage: Amphotericin B should be kept in a tightly closed container, protected from light, and stored at a temperature between 2 and 8 ?C. Labelling: The designation Amphotericin B for parenteral use indicates that the substance complies with the altered and additional requirements for Amphotericin B and may be used for parenteral administration. Additional information: Even in the absence of light, Amphotericin B is gradually degraded on exposure to a humid atmosphere, the decomposition being faster at higher temperatures. In diluted solutions it is sensitive to light and is inactivated at low pH values. Definition: Amphotericin B contains not less than 750 μg per mg, calculated with reference to the dried substance.
CHEBI
2682
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
RS_ITEM_NUM
1032007
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
ChEMBL
CHEMBL267345
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
FDA UNII
7XU7A7DROE
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
EVMPD
SUB05486MIG
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
EVMPD
SUB20545
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
EPA CompTox
DTXSID9022601
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
INN
869
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
PUBCHEM
5280965
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
EVMPD
SUB12887MIG
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
DAILYMED
7XU7A7DROE
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
DRUG BANK
DB00681
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
EVMPD
SUB119245
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
NCI_THESAURUS
C238
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
MESH
D000666
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
RXCUI
42527
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
ALTERNATIVE
SMS_ID
100000092100
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
MERCK INDEX
m1852
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY Merck Index
HSDB
3008
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
LACTMED
Amphotericin B
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
CAS
1397-89-3
Created by admin on Fri Dec 15 15:02:58 UTC 2023 , Edited by admin on Fri Dec 15 15:02:58 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of Amphotericin B
SALT/SOLVATE (PARENT)
Structure of Amphotericin B deoxycholate
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
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