RUCAPARIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H18FN3O
Molecular Weight	323.3641
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of RUCAPARIB

Structure Search

SMILES

CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(F)=CC(N2)=C34

InChI

InChIKey=HMABYWSNWIZPAG-UHFFFAOYSA-N

InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24)

HIDE SMILES / InChI

Approval Year

Name

Type

Language

RUCAPARIB

Official Name

English

6H-AZEPINO(5,4,3-CD)INDOL-6-ONE, 8-FLUORO-1,3,4,5-TETRAHYDRO-2-(4-((METHYLAMINO)METHYL)PHENYL)-

Systematic Name

English

RUCAPARIB [USAN]

Common Name

English

rucaparib [INN]

Common Name

English

6H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-6-ONE, 8-FLUORO-1,3,4,5-TETRAHYDRO-2-(4-((METHYLAMINO)METHYL)PHENYL)-

Systematic Name

English

Rucaparib [WHO-DD]

Common Name

English

AG-14447

Code

English

8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-1,3,4,5-TETRAHYDRO-6H-AZEPINO(5,4,3-CD)INDOL-6-ONE

Systematic Name

English

RUCAPARIB [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C62554

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

WHO-ATC

L01XX55

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

NDF-RT

N0000191623

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

FDA ORPHAN DRUG

374712

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

EU-Orphan Drug

EU/3/12/1049

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

Code System Code Type Description

FDA UNII

8237F3U7EH

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

EVMPD

SUB74859

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

DRUG BANK

DB12332

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

PUBCHEM

9931954

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

DRUG CENTRAL

5203

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

CHEBI

134689

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

ChEMBL

CHEMBL1173055

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

RXCUI

1862579

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

CAS

283173-50-2

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

USAN

XX-94

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

INN

9471

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

LACTMED

Rucaparib

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

NCI_THESAURUS

C137800

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

EPA CompTox

DTXSID10182563

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

MERCK INDEX

m11980

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

DAILYMED

8237F3U7EH

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

WIKIPEDIA

RUCAPARIB

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

SMS_ID

100000136799

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

NDF-RT

N0000191622

Created by admin on Sat Dec 16 00:25:47 UTC 2023 , Edited by admin on Sat Dec 16 00:25:47 UTC 2023

PRIMARY

Poly(ADP-Ribose) Polymerase Inhibitors [MoA]

ACTIVE MOIETY


					8237F3U7EH

RUCAPARIB

METABOLITE (PARENT)


					D57RNL9EV6

4-(8-FLUORO-6-METHYL-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZOIC ACID

METABOLITE (PARENT)


					53BKY5NTL7

BENZAMIDE, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-N-METHYL-

METABOLITE (PARENT)


					V2GJ2XVK6G

BENZOIC ACID, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-

METABOLITE (PARENT)


					4K3MM9XEJ2

6H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-6-ONE, 2-(4-(AMINOMETHYL)PHENYL)-8-FLUORO-1,3,4,5-TETRAHYDRO-

METABOLITE (PARENT)


					HCF2D2KJ6Y

N-(4-(8-FLUORO-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZYL)FORMAMIDE

SALT/SOLVATE (PARENT)


					41AX9SJ8KO

RUCAPARIB CAMSYLATE

SALT/SOLVATE (PARENT)


					H3M9955244

RUCAPARIB PHOSPHATE