ENZALUTAMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H16F4N4O2S
Molecular Weight	464.436
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ENZALUTAMIDE

Structure Search

SMILES

CNC(=O)C1=CC=C(C=C1F)N2C(=S)N(C(=O)C2(C)C)C3=CC(=C(C=C3)C#N)C(F)(F)F

InChI

InChIKey=WXCXUHSOUPDCQV-UHFFFAOYSA-N

InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)

HIDE SMILES / InChI

Approval Year

Name

Type

Language

ENZALUTAMIDE

Official Name

English

ENZALUTAMIDE [USAN]

Common Name

English

4-(3-(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)-5,5-DIMETHYL-4-OXO-2-THIOXOIMIDAZOLIDIN-1-YL)-2-FLUORO-N-METHYLBENZAMIDE

Systematic Name

English

Enzalutamide [WHO-DD]

Common Name

English

ENZALUTAMIDE [JAN]

Common Name

English

XTANDI

Brand Name

English

MDV 3100

Common Name

English

MDV-3100

Code

English

enzalutamide [INN]

Common Name

English

MDV3100

Code

English

ENZALUTAMIDE [VANDF]

Common Name

English

ENZALUTAMIDE [MI]

Common Name

English

BENZAMIDE, 4-(3-(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)-5,5-DIMETHYL-4-OXO-2-THIOXO-1-IMIDAZOLIDINYL)-2-FLUORO-N-METHYL-

Systematic Name

English

ENZALUTAMIDE [ORANGE BOOK]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C146993

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

NDF-RT

N0000175560

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

LIVERTOX

NBK548070

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

WHO-ATC

L02BB04

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

Code System Code Type Description

IUPHAR

6812

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

PUBCHEM

15951529

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

WIKIPEDIA

Enzalutamide

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

EPA CompTox

DTXSID10912307

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

FDA UNII

93T0T9GKNU

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

SMS_ID

100000138095

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

DAILYMED

93T0T9GKNU

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

NDF-RT

N0000185507

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

Cytochrome P450 2C9 Inducers [MoA]

ChEMBL

CHEMBL1082407

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

DRUG BANK

DB08899

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

INN

9621

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

USAN

WW-149

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

DRUG CENTRAL

4628

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

CHEBI

68534

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

MESH

C540278

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

EVMPD

SUB77412

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

CAS

915087-33-1

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

RXCUI

1307298

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

RxNorm

NDF-RT

N0000185607

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

Cytochrome P450 2C19 Inducers [MoA]

NDF-RT

N0000185506

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

Cytochrome P450 3A4 Inducers [MoA]

NCI_THESAURUS

C71744

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

MERCK INDEX

m11683

Created by admin on Fri Dec 15 16:30:25 UTC 2023 , Edited by admin on Fri Dec 15 16:30:25 UTC 2023

PRIMARY

ACTIVE MOIETY


					93T0T9GKNU

METABOLITE (PARENT)


					5MK9M4BF22

4-(3-(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)-5,5-DIMETHYL-2,4-DIOXO-1-IMIDAZOLIDINYL)-2-FLUOROBENZOIC ACID

METABOLITE (PARENT)


					DTM3GJC5NY

4-(3-(4-CARBAMOYL-3-(TRIFLUOROMETHYL)PHENYL)-5,5-DIMETHYL-4-OXO-2-THIOXO-IMIDAZOLIDIN-1-YL)-2-FLUORO-BENZOIC ACID

METABOLITE (PARENT)


					HZ7ZZC4TC6

4-(3-(4-(AMINOCARBONYL)-3-(TRIFLUOROMETHYL)PHENYL)-5,5-DIMETHYL-4-OXO-2-THIOXO-1-IMIDAZOLIDINYL)-2-FLUORO-N-METHYLBENZAMIDE

METABOLITE (PARENT)


					KLY798P76T

BENZAMIDE, 4-(3-(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)-5,5-DIMETHYL-4-OXO-2-THIOXO-1-IMIDAZOLIDINYL)-2-FLUORO-N-(HYDROXYMETHYL)-

METABOLITE INACTIVE (PARENT)


					YF8MAL2HDY

ENZALUTAMIDE CARBOXYLIC ACID