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Details

Stereochemistry ACHIRAL
Molecular Formula C21H16ClF3N4O3
Molecular Weight 464.825
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SORAFENIB

SMILES

CNC(=O)C1=CC(OC2=CC=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)=CC=N1

InChI

InChIKey=MLDQJTXFUGDVEO-UHFFFAOYSA-N
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
SORAFENIB
EMA EPAR   INN   MART.   MI   USAN   VANDF   WHO-DD  
INN   USAN  
Official Name English
SORAFENIB [USAN]
Common Name English
SORAFENIB [MART.]
Common Name English
SORAFENIB [EMA EPAR]
Common Name English
2-PYRIDINECARBOXAMIDE, 4-(4-((((4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)AMINO)CARBONYL)AMINO)PHENOXY)-N-METHYL-
Systematic Name English
BAY 43-9006
Code English
SORAFENIB [MI]
Common Name English
4-(4-(3-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREIDO)PHENOXY)-N(SUP 2)-METHYLPYRIDINE-2-CARBOXAMIDE
Systematic Name English
Sorafenib [WHO-DD]
Common Name English
SORAFENIB [VANDF]
Common Name English
BAY-43-9006
Code English
sorafenib [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129825
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
WHO-VATC QL01XE05
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
NCI_THESAURUS C1742
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
WHO-ATC L01XE05
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
NDF-RT N0000175076
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
FDA ORPHAN DRUG 675918
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
FDA ORPHAN DRUG 220206
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
FDA ORPHAN DRUG 185204
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
EMA ASSESSMENT REPORTS NEXAVAR (AUTHORIZED: CARCINOMA, HEPATOCELLULAR, CARINOMA, RENAL CELL)
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
FDA ORPHAN DRUG 320310
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
LIVERTOX NBK548944
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
FDA ORPHAN DRUG 229206
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
NDF-RT N0000175605
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
NCI_THESAURUS C1404
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
Code System Code Type Description
INN
8234
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
RXCUI
495881
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY RxNorm
LACTMED
Sorafenib
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
NCI_THESAURUS
C61948
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
MESH
C471405
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
PUBCHEM
216239
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
EPA CompTox
DTXSID7041128
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
USAN
UU-02
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
WIKIPEDIA
SORAFENIB
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
ChEMBL
CHEMBL1336
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
HSDB
8173
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
IUPHAR
5711
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
DRUG BANK
DB00398
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
DRUG CENTRAL
2459
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
FDA UNII
9ZOQ3TZI87
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
MERCK INDEX
m10116
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY Merck Index
CHEBI
50924
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
SMS_ID
100000091433
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
CAS
284461-73-0
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
EVMPD
SUB23139
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
DAILYMED
9ZOQ3TZI87
Created by admin on Sat Dec 16 04:53:43 UTC 2023 , Edited by admin on Sat Dec 16 04:53:43 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of SORAFENIB
METABOLITE (PARENT)
Structure of BAY-439007
METABOLITE (PARENT)
Structure of BAY-72-1974
METABOLITE (PARENT)
Structure of BAY-721973
METABOLITE (PARENT)
Structure of BAY-68-7769
METABOLITE ACTIVE (PARENT)
Structure of BAY-673472
SALT/SOLVATE (PARENT)
Structure of SORAFENIB TOSYLATE
NIH
NCATS
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