AXITINIB

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H18N4OS
Molecular Weight	386.47
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(\C=C\C4=CC=CC=N4)=NN3

InChI

InChIKey=RITAVMQDGBJQJZ-FMIVXFBMSA-N

InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+

HIDE SMILES / InChI

Approval Year

Name

Type

Language

AXITINIB

Official Name

English

N-METHYL-2-(3-((E)-2-PYRIDIN-2-YL-VINYL)-1H-INDAZOL-6-YLSULFANYL)-BENZAMIDE

Systematic Name

English

AXITINIB [VANDF]

Common Name

English

AG-013736

Code

English

AXITINIB [ORANGE BOOK]

Common Name

English

AXITINIB [MI]

Common Name

English

Axitinib [WHO-DD]

Common Name

English

axitinib [INN]

Common Name

English

NSC-757441

Code

English

AG-13736

Code

English

AXITINIB [MART.]

Common Name

English

BENZAMIDE, N-METHYL-2-((3-((1E)-2-(2-PYRIDINYL)ETHENYL)-1H-INDAZOL-6-YL)THIO)-

Systematic Name

English

AXITINIB [JAN]

Common Name

English

INLYTA

Brand Name

English

N-METHYL-2((3-((1E0-2-(PYRIDIN-2-YL)ETHENYL)-1H-INAZOL-6-YLSUFANYL)BENZAMIDE

Common Name

English

AXITINIB [USAN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

L01XE17

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

NCI_THESAURUS

C1742

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

EMA ASSESSMENT REPORTS

INLYTA (AUTHORIZED: CARCINOMA, CANCER CELL)

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

FDA ORPHAN DRUG

730120

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

WHO-VATC

QL01XE17

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

NCI_THESAURUS

C93259

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

NDF-RT

N0000175605

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

NCI_THESAURUS

C129825

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

FDA ORPHAN DRUG

230706

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

EU-Orphan Drug

EU/3/10/844

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

LIVERTOX

NBK548139

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

FDA ORPHAN DRUG

240607

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

Code System Code Type Description

DRUG CENTRAL

4225

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

WIKIPEDIA

Axitinib

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

RXCUI

1242999

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

RxNorm

EPA CompTox

DTXSID3049049

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

MESH

C503983

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

LACTMED

Axitinib

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

PUBCHEM

6450551

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

MERCK INDEX

m2153

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

Merck Index

FDA UNII

C9LVQ0YUXG

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

SMS_ID

100000089442

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

EVMPD

SUB25427

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

ChEMBL

CHEMBL1289926

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

NDF-RT

N0000020000

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

Receptor Tyrosine Kinase Inhibitors [MoA]

NSC

757441

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

IUPHAR

5659

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

USAN

RR-15

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

INN

8720

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

DRUG BANK

DB06626

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

DAILYMED

C9LVQ0YUXG

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

CHEBI

66910

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

NCI_THESAURUS

C38718

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

CAS

319460-85-0

Created by admin on Fri Dec 15 16:19:06 UTC 2023 , Edited by admin on Fri Dec 15 16:19:06 UTC 2023

PRIMARY

ACTIVE MOIETY


					C9LVQ0YUXG

AXITINIB

METABOLITE (PARENT)


					VFJ6UZ972A

N-METHYL-2-((3-(3-(2-PYRIDYL)OXIRAN-2-YL)-1H-INDAZOL-6-YL)SULFANYL)BENZAMIDE

METABOLITE (PARENT)


					9AQ388RV8M

N-METHYL-2-((3-((E)-2-(1-OXIDOPYRIDIN-1-IUM-2-YL)VINYL)-1H-INDAZOL-6-YL)SULFANYL)BENZAMIDE

METABOLITE (PARENT)


					O2E9E70NTE

SULFONYL AXITINIB

METABOLITE (PARENT)


					6ID0Q0B0IK

AXITINIB SULFOXIDE PYRIDINE-N-OXIDE

METABOLITE (PARENT)


					M3MW1SN0H4

N-DEMETHYL-N-(HYDROXYMETHYL)AXITINIB

METABOLITE (PARENT)


					55P8GY3IEK

AXITINIB SULFOXIDE

METABOLITE INACTIVE (PARENT)


					I7W61FSA1A

PF-04621675