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Details

Stereochemistry ACHIRAL
Molecular Formula C24H29N7O2
Molecular Weight 447.5328
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PALBOCICLIB

SMILES

CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O

InChI

InChIKey=AHJRHEGDXFFMBM-UHFFFAOYSA-N
InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
PALBOCICLIB
DASH   INN   USAN   WHO-DD  
INN   USAN  
Official Name English
Palbociclib [WHO-DD]
Common Name English
PALBOCICLIB [MI]
Common Name English
6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-((5-(PIPERAZIN-1-YL)PYRIDIN-2-YL)AMINO)-8H-PYRIDO(2,3-D)PYRIMIDIN-7-ONE
Systematic Name English
IBRANCE
Brand Name English
PYRIDO(2,3-D)PYRIMIDIN-7(8H)-ONE, 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-((5-(1-PIPERAZINYL)-2-PYRIDINYL)AMINO)-
Systematic Name English
6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-((5-(PIPERAZIN-1-YL)PYRIDIN-2-YL)AMINO(PYRIDO(2,3-D)PYRIMIDIN-7(8H)-ONE
Common Name English
PALBOCICLIB [USAN]
Common Name English
PALBOCICLIB [JAN]
Common Name English
PD-0332991
Code English
palbociclib [INN]
Common Name English
PALBOCICLIB [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
WHO-ATC L01XE33
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
FDA ORPHAN DRUG 781420
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
NCI_THESAURUS C2185
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
NCI_THESAURUS C129825
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
NDF-RT N0000175605
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
Code System Code Type Description
FDA UNII
G9ZF61LE7G
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
MERCK INDEX
m11849
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
EVMPD
SUB177204
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
CHEBI
85993
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
NDF-RT
N0000175082
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY Kinase Inhibitors [MoA]
EPA CompTox
DTXSID40972590
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
NCI_THESAURUS
C49176
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
ChEMBL
CHEMBL189963
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
NDF-RT
N0000190114
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY Cytochrome P450 3A Inhibitors [MoA]
RXCUI
1601374
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY RxNorm
USAN
ZZ-152
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
SMS_ID
100000163078
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
PUBCHEM
5330286
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
DAILYMED
G9ZF61LE7G
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
INN
9802
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
WIKIPEDIA
Palbociclib
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
LACTMED
Palbociclib
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
CAS
571190-30-2
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
DRUG CENTRAL
4941
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
DRUG BANK
DB09073
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
IUPHAR
7380
Created by admin on Fri Dec 15 19:38:50 UTC 2023 , Edited by admin on Fri Dec 15 19:38:50 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of PALBOCICLIB
SALT/SOLVATE (PARENT)
Structure of PALBOCICLIB ISETHIONATE
SALT/SOLVATE (PARENT)
Structure of PALBOCICLIB HYDROCHLORIDE
NIH
NCATS
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