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Details

Stereochemistry ACHIRAL
Molecular Formula C27H29N5O6S.H2O
Molecular Weight 569.629
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BOSENTAN

SMILES

O.COC1=CC=CC=C1OC2=C(OCCO)N=C(N=C2NS(=O)(=O)C3=CC=C(C=C3)C(C)(C)C)C4=NC=CC=N4

InChI

InChIKey=SXTRWVVIEPWAKM-UHFFFAOYSA-N
InChI=1S/C27H29N5O6S.H2O/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24;/h5-15,33H,16-17H2,1-4H3,(H,30,31,32);1H2

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
BOSENTAN
ORANGE BOOK   USAN   USP-RS   VANDF  
USAN  
Official Name English
BOSENTAN [USP-RS]
Common Name English
BOSENTAN MONOHYDRATE [MI]
Common Name English
RO-47-0203-029
Code English
P-TERT-BUTYL-N-(6-(2-HYDROXYETHOXY)-5-(O-METHOXYPHENOXY)-2-(2-PYRIMIDINYL)-4-PYRIMIDINYL)BENZENESULFONAMIDE MONOHYDRATE
Common Name English
BOSENTAN [USAN]
Common Name English
BOSENTAN MONOHYDRATE [EMA EPAR]
Common Name English
RO 47-0203/029
Code English
RO-470203029
Code English
TRACLEER
Brand Name English
BENZENESULFONAMIDE, 4-(1,1-DIMETHYLETHYL)-N-(6-(2-HYDROXYETHOXY)-5-(2-METHOXYPHENOXY)(2,2'BIPYRIMIDIN)-4-YL)-, MONOHYDRATE
Systematic Name English
BOSENTAN [VANDF]
Common Name English
BOSENTAN HYDRATE [JAN]
Common Name English
BOSENTAN [ORANGE BOOK]
Common Name English
Bosentan monohydrate [WHO-DD]
Common Name English
BOSENTAN MONOHYDRATE
EMA EPAR   MI   WHO-DD  
Common Name English
BOSENTAN HYDRATE
JAN  
Common Name English
RO-47-0203/029
Code English
Classification Tree Code System Code
NDF-RT N0000175581
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
WHO-VATC QC02KX01
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
FDA ORPHAN DRUG 134200
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
LIVERTOX NBK547999
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
EMA ASSESSMENT REPORTS STAYVEER (AUTHORIZED SCLERODERMA, SYSTEMIC
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
WHO-ATC C02KX01
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
EMA ASSESSMENT REPORTS TRACLEER (AUTHORIZED: PLUMONARY HYPERTENSION, SYSTEMATIC SCLERODERMA)
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
FDA ORPHAN DRUG 267608
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
FDA ORPHAN DRUG 292209
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
EU-Orphan Drug EU/3/03/139
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
Code System Code Type Description
MERCK INDEX
m2625
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY Merck Index
CAS
157212-55-0
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
LACTMED
Bosentan
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
PUBCHEM
185462
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
RXCUI
498193
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
ALTERNATIVE
USAN
HH-16
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
RS_ITEM_NUM
1076115
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
EVMPD
SUB22249
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
DAILYMED
Q326023R30
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
SMS_ID
100000091512
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
IUPHAR
3494
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
EPA CompTox
DTXSID80873178
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
WIKIPEDIA
BOSENTAN
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
CHEBI
51450
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
RXCUI
75207
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
DRUG CENTRAL
392
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
FDA UNII
Q326023R30
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
MESH
C086232
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
NCI_THESAURUS
C47417
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
DRUG BANK
DB00559
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
ChEMBL
CHEMBL957
Created by admin on Fri Dec 15 15:33:54 UTC 2023 , Edited by admin on Fri Dec 15 15:33:54 UTC 2023
PRIMARY
SUBSTANCE RECORD
Structure of BOSENTAN
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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