SAQUINAVIR MESYLATE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C38H50N6O5.CH4O3S
Molecular Weight	766.946
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SAQUINAVIR MESYLATE

Structure Search

SMILES

CS(O)(=O)=O.[H][C@@]12CCCC[C@]1([H])CN(C[C@@H](O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(N)=O)NC(=O)C4=CC=C5C=CC=CC5=N4)[C@@H](C2)C(=O)NC(C)(C)C

InChI

InChIKey=IRHXGOXEBNJUSN-YOXDLBRISA-N

InChI=1S/C38H50N6O5.CH4O3S/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29;1-5(2,3)4/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49);1H3,(H,2,3,4)/t26-,27+,30-,31-,32-,33+;/m0./s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

SAQUINAVIR MESYLATE

Official Name

English

SAQUINAVIR MESILATE [EP MONOGRAPH]

Common Name

English

SAQUINAVIR MESYLATE [USP MONOGRAPH]

Common Name

English

(S)-N-((.ALPHA.S)-.ALPHA.-((1R)-2-((3S,4AS,8AS)-3-(TERT-BUTYLCARBAMOYL)OCTAHYDRO-2(1H)-ISOQUINOLYL)-1-HYDROXYETHYL)PHENETHYL)-2-QUINALDAMIDOSUCCINAMIDE MONOMETHANESULFONATE

Common Name

English

RO 31-8959/003

Code

English

SAQUINAVIR METHANESULFONATE SALT [MI]

Common Name

English

SAQUINAVIR MESYLATE [USP-RS]

Common Name

English

SAQUINAVIR MESILATE [JAN]

Common Name

English

Saquinavir mesilate [WHO-DD]

Common Name

English

SAQUINAVIR MESYLATE [USP IMPURITY]

Common Name

English

SAQUINAVIR MESILATE [MART.]

Common Name

English

SAQUINAVIR MESYLATE [VANDF]

Common Name

English

SAQUINAVIR MESILATE

Common Name

English

RO-318959003

Code

English

RO-31-8959/003

Code

English

SAQUINAVIR MESYLATE [USAN]

Common Name

English

BUTANEDIAMIDE, N(SUP 1)-(3-(3-(((1,1-DIMETHYLETHYL)AMINO)CARBONYL)OCTAHYDRO-2(1H)-ISOQUINOLINYL)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-2-((2-QUINOLINYLCARBONYL)AMINO)-, (3S-(2(1R*(R*),2S*),3.ALPHA.,4A.BETA.,8A.BETA.))-, MONOMETHANESULPHONATE

Common Name

English

BUTANEDIAMIDE, N(SUP 1)-(3-(3-(((1,1-DIMETHYLETHYL)AMINO)CARBONYL)OCTAHYDRO-2(1H)-ISOQUINOLINYL)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-2-((2-QUINOLINYLCARBONYL)AMINO)-, (3S-(2(1R*(R*),2S*),3.ALPHA.,4A.BETA.,8A.BETA.))-, MONOMETHANESULFONATE

Common Name

English

(S)-N-((.ALPHA.S)-.ALPHA.-((1R)-2-((3S,4AS,8AS)-3-(TERT-BUTYLCARBAMOYL)OCTAHYDRO-2(1H)-ISOQUINOLYL)-1-HYDROXYETHYL)PHENETHYL)-2-QUINALDAMIDOSUCCINAMIDE MONOMETHANESULPHONATE

Common Name

English

SAQUINAVIR MESILATE [WHO-IP]

Common Name

English

SAQUINAVIR MESYLATE [ORANGE BOOK]

Common Name

English

SAQUINAVIR METHANESULFONATE SALT

Common Name

English

INVIRASE

Brand Name

English

Classification Tree Code System Code

EMA ASSESSMENT REPORTS

INVIRASE (AUTHORIZED: HIV INFECTIONS)

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

NCI_THESAURUS

C97366

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

Code System Code Type Description

WHO INTERNATIONAL PHARMACOPEIA

SAQUINAVIR MESYLATE

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

PRIMARY

Description: A white or almost white powder. Solubility: Very slightly soluble in water and sparingly soluble in methanol R. Category: Antiretroviral (Protease Inhibitor). Storage: Saquinavir mesilate should be kept in a tightly-closed container, protected from light. Additional information: Saquinavir mesilate is slightly hygroscopic. Definition: Saquinavir mesilate contains not less than 98.5 % and not more than 101.0 % of C38H50N6O5.CH4O3S calculated with reference to the dried substance. Manufacture: The production method must be evaluated to determine the potential for formation of alkyl mesilates, which is particularly likely to occur if the reaction medium contains lower alcohols. Where necessary, the production method is validated to demonstrate that alkyl mesilates are not detectable in the final product.

RXCUI

859857

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

PRIMARY

RxNorm

DAILYMED

UHB9Z3841A

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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RS_ITEM_NUM

1609829

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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SMS_ID

100000091808

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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CAS

149845-06-7

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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NCI_THESAURUS

C1602

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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USAN

GG-17

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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FDA UNII

UHB9Z3841A

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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PUBCHEM

60934

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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EVMPD

SUB12572MIG

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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EPA CompTox

DTXSID9023835

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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MERCK INDEX

m9776

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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Merck Index

DRUG BANK

DBSALT002836

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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ChEMBL

CHEMBL114

Created by admin on Fri Dec 15 15:41:37 UTC 2023 , Edited by admin on Fri Dec 15 15:41:37 UTC 2023

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ACTIVE MOIETY


					L3JE09KZ2F

SUBSTANCE RECORD


					UHB9Z3841A

SAQUINAVIR MESYLATE