U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C51H79NO13
Molecular Weight 914.1719
Optical Activity UNSPECIFIED
Defined Stereocenters 15 / 15
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SIROLIMUS

SMILES

[H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]4CC[C@@H](O)[C@@H](C4)OC

InChI

InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N
InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
SIROLIMUS
EMA EPAR   HSDB   INN   MART.   ORANGE BOOK   USAN   VANDF   WHO-DD  
INN   USAN  
Official Name English
SIROLIMUS [VANDF]
Common Name English
EVEROLIMUS IMPURITY A [EP IMPURITY]
Common Name English
AY-22989
Code English
SM-88 COMPONENT SIROLIMUS
Code English
Sirolimus [WHO-DD]
Common Name English
WY-090217
Code English
RAPAMYCIN [MI]
Common Name English
SIROLIMUS [JAN]
Common Name English
NSC-226080
Code English
NAB-RAPAMYCIN COMPONENT RAPAMYCIN
Common Name English
SIROLIMUS [HSDB]
Common Name English
RPM
Common Name English
L04AA10
Code English
RAPA
Common Name English
sirolimus [INN]
Common Name English
SIROLIMUS [ORANGE BOOK]
Common Name English
NPC-12G
Common Name English
FYARRO
Brand Name English
SIROLIMUS [USP-RS]
Common Name English
RAPAMYCIN
MI  
Common Name English
HYFTOR
Brand Name English
SIROLIMUS [USAN]
Common Name English
RAPAMUNE
Brand Name English
SIROLIMUS [EMA EPAR]
Common Name English
RAPALIMUS
Brand Name English
SIROLIMUS [MART.]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 434114
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 568416
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 524916
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 616217
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 453114
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
WHO-VATC QL04AA10
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 327210
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
NCI_THESAURUS C261
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 698619
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 379312
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
NDF-RT N0000175624
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
NCI_THESAURUS C574
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 828521
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 184304
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
EU-Orphan Drug EU/3/17/1910
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 237007
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
NDF-RT N0000175605
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 391013
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
LIVERTOX NBK548028
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 540516
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
NDF-RT N0000175550
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 678319
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 469915
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 628918
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 508515
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 833821
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
EMA ASSESSMENT REPORTS RAPAMUNE (AUTHORIZED: GRAFT REJECTION)
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 829421
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
NDF-RT N0000175625
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
WHO-ATC S01XA23
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
CFR 21 CFR 862.3840
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
EMA ASSESSMENT REPORTS RAPAMUNE (AUTHORIZED: KINDEY TRANSPLANTATION)
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
FDA ORPHAN DRUG 555516
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
WHO-ATC L04AA10
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
Code System Code Type Description
MESH
D020123
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
MERCK INDEX
m9502
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY Merck Index
DAILYMED
W36ZG6FT64
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
IUPHAR
6031
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
NSC
226080
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
RS_ITEM_NUM
1612765
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
USAN
DD-70
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
SMS_ID
100000089170
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
EVMPD
SUB10537MIG
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
INN
7104
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
NCI_THESAURUS
C1212
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
CHEBI
9168
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
ChEMBL
CHEMBL413
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
RXCUI
35302
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY RxNorm
HSDB
7284
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
LACTMED
Sirolimus
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
PUBCHEM
5284616
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
FDA UNII
W36ZG6FT64
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
WIKIPEDIA
SIROLIMUS
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
DRUG BANK
DB00877
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
JAPANESE REVIEW
RAPALIMUS
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY APPROVED JULY 2014
DRUG CENTRAL
2446
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
CAS
53123-88-9
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
EPA CompTox
DTXSID5023582
Created by admin on Fri Dec 15 15:41:41 UTC 2023 , Edited by admin on Fri Dec 15 15:41:41 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of SIROLIMUS
METABOLITE ACTIVE (PARENT)
Structure of NOVOLIMUS
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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