COPANLISIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H28N8O4
Molecular Weight	480.5196
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of COPANLISIB

Structure Search

SMILES

COC1=C(OCCCN2CCOCC2)C=CC3=C1N=C(NC(=O)C4=CN=C(N)N=C4)N5CCN=C35

InChI

InChIKey=PZBCKZWLPGJMAO-UHFFFAOYSA-N

InChI=1S/C23H28N8O4/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15/h3-4,13-14H,2,5-12H2,1H3,(H2,24,26,27)(H,28,29,32)

HIDE SMILES / InChI

Approval Year

Name

Type

Language

COPANLISIB

Official Name

English

2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE-5-CARBOXAMIDE

Common Name

English

COPANLISIB [MI]

Common Name

English

BAY-80-6946

Code

English

2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE-5-CARBOXAMIDE

Systematic Name

English

BAY80-6946

Code

English

copanlisib [INN]

Common Name

English

5-PYRIMIDINECARBOXAMIDE, 2-AMINO-N-(2,3-DIHYDRO-7-METHOXY-8-(3-(4-MORPHOLINYL)PROPOXY)IMIDAZO(1,2-C)QUINAZOLIN-5-YL)-

Systematic Name

English

BAY 80-6946

Code

English

COPANLISIB [USAN]

Common Name

English

Copanlisib [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

FDA ORPHAN DRUG

463314

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

WHO-ATC

L01XX61

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

FDA ORPHAN DRUG

811321

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

FDA ORPHAN DRUG

552416

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

NCI_THESAURUS

C2152

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

FDA ORPHAN DRUG

811421

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

FDA ORPHAN DRUG

552616

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

NDF-RT

N0000175605

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

FDA ORPHAN DRUG

552516

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

EU-Orphan Drug

EU/3/18/2064

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

Code System Code Type Description

SMS_ID

100000170809

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

NCI_THESAURUS

C96796

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

PUBCHEM

24989044

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

MERCK INDEX

m12036

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

WIKIPEDIA

Copanlisib

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

EVMPD

SUB184952

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

RXCUI

1945077

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

DRUG CENTRAL

5256

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

ChEMBL

CHEMBL3218576

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

FDA UNII

WI6V529FZ9

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

CAS

1032568-63-0

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

DAILYMED

WI6V529FZ9

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

LACTMED

Copanlisib

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

USAN

CD-71

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

INN

9726

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

DRUG BANK

DB12483

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

CHEBI

173077

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

EPA CompTox

DTXSID00145728

Created by admin on Fri Dec 15 17:26:49 UTC 2023 , Edited by admin on Fri Dec 15 17:26:49 UTC 2023

PRIMARY

ACTIVE MOIETY


					WI6V529FZ9

METABOLITE (PARENT)


					QY9D7067E8

2-AMINO-N-(2,3-DIHYDRO-8-HYDROXY-7-METHOXYIMIDAZO(1,2-C)QUINAZOLIN-5-YL)-5-PYRIMIDINECARBOXAMIDE

METABOLITE (PARENT)


					RTW1LKQ7TC

2-AMINO-N-(8-(3-(FORMYL(2-HYDROXYETHYL)AMINO)PROPOXY)-2,3-DIHYDRO-7-METHOXYIMIDAZO(1,2-C)QUINAZOLIN-5-YL)-5-PYRIMIDINECARBOXAMIDE

METABOLITE (PARENT)


					QYB71X85N4

2-AMINO-N-(2,3-DIHYDRO-8-(3-((2-HYDROXYETHYL)AMINO)PROPOXY)-7-METHOXYIMIDAZO(1,2-C)QUINAZOLIN-5-YL)-5-PYRIMIDINECARBOXAMIDE

METABOLITE (PARENT)


					7D3BZM3BQN

3-((5-(2-AMINOPYRIMIDINE-5-CARBOXAMIDO)-7-METHOXY-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-8-YL)OXY)PROPANOIC ACID

METABOLITE (PARENT)


					GC91Z6YS52

2-AMINO-N-(8-(3-HYDROXYPROPOXY)-7-METHOXY-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE-5-CARBOXAMIDE

METABOLITE ACTIVE (PARENT)


					UD5QDA5GMW

SALT/SOLVATE (PARENT)


					W421JK3CPA

COPANLISIB HYDROCHLORIDE HYDRATE

SALT/SOLVATE (PARENT)


					03ZI7RZ52O

COPANLISIB HYDROCHLORIDE