Olaparib

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H23FN4O3
Molecular Weight	434.4628
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of Olaparib

Structure Search

SMILES

FC1=CC=C(CC2=NNC(=O)C3=CC=CC=C23)C=C1C(=O)N4CCN(CC4)C(=O)C5CC5

InChI

InChIKey=FDLYAMZZIXQODN-UHFFFAOYSA-N

InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)

HIDE SMILES / InChI

Approval Year

Name

Type

Language

Olaparib

Official Name

English

Olaparib [WHO-DD]

Common Name

English

AZD2281

Code

English

KEYLYNK-010 COMPONENT OLAPARIB

Code

English

OLAPARIB [USAN]

Common Name

English

OLAPARIB [ORANGE BOOK]

Common Name

English

NSC-747856

Code

English

OLAPARIB [JAN]

Common Name

English

AZ2281

Code

English

OLAPARIB [VANDF]

Common Name

English

KU-0059436

Code

English

olaparib [INN]

Common Name

English

1(2H)-Phthalazinone, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-

Systematic Name

English

PIPERAZINE, 1-(CYCLOPROPYLCARBONYL)-4-(5-((3,4-DIHYDRO-4-OXO-1-PHTHALAZINYL)METHYL)-2-FLUOROBENZOYL)-

Systematic Name

English

LYNPARZA

Brand Name

English

4-[(3-{[4-(Cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorophenyl)methyl]phthalazin-1(2H)-one

Systematic Name

English

AZD-2281

Code

English

OLAPARIB [MI]

Common Name

English

KU-59436

Code

English

OLAPARIB COMPONENT OF KEYLYNK-010

Code

English

OLAPARIB [MART.]

Common Name

English

AZ-2281

Code

English

Classification Tree Code System Code

NDF-RT

N0000191623

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

EMA ASSESSMENT REPORTS

LYNPARZA (AUTHORIZED: OVARIAN NEOPLASMS)

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

FDA ORPHAN DRUG

419013

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

FDA ORPHAN DRUG

417613

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

EU-Orphan Drug

EU/3/07/501

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

FDA ORPHAN DRUG

409213

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

WHO-ATC

L01XX46

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

FDA ORPHAN DRUG

655318

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

NCI_THESAURUS

C62554

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

Code System Code Type Description

DAILYMED

WOH1JD9AR8

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

EVMPD

SUB32234

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

SMS_ID

100000124466

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

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MERCK INDEX

m8185

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

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Merck Index

ChEMBL

CHEMBL521686

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

DRUG CENTRAL

4907

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

NCI_THESAURUS

C71721

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

NSC

747856

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

INN

8685

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

RXCUI

1597582

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

RxNorm

IUPHAR

7519

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

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FDA UNII

WOH1JD9AR8

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

CAS

763113-22-0

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

PUBCHEM

23725625

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

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DRUG BANK

DB09074

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

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MESH

C531550

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

CHEBI

83766

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

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LACTMED

Olaparib

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

WIKIPEDIA

OLAPARIB

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

EPA CompTox

DTXSID60917988

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

NDF-RT

N0000191622

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

Poly(ADP-Ribose) Polymerase Inhibitors [MoA]

USAN

BC-28

Created by admin on Fri Dec 15 15:37:57 UTC 2023 , Edited by admin on Fri Dec 15 15:37:57 UTC 2023

PRIMARY

ACTIVE MOIETY


					WOH1JD9AR8

Olaparib

SALT/SOLVATE (PARENT)


					34FMX7983W

Olaparib monohydrate

SALT/SOLVATE (PARENT)


					Q67E7B7KG6

Olaparib hemi-2-propanol