UPROSERTIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H16Cl2F2N4O2
Molecular Weight	429.248
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of UPROSERTIB

Structure Search

SMILES

CN1N=CC(Cl)=C1C2=C(Cl)OC(=C2)C(=O)N[C@H](CN)CC3=CC=C(F)C(F)=C3

InChI

InChIKey=AXTAPYRUEKNRBA-JTQLQIEISA-N

InChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

UPROSERTIB

Official Name

English

AKT INHIBITOR GSK-2141795

Common Name

English

2-FURANCARBOXAMIDE, N-((1S)-2-AMINO-1-((3,4-DIFLUOROPHENYL)METHYL)ETHYL)-5-CHLORO-4-(4-CHLORO-1-METHYL-1H-PYRAZOL-5-YL)-

Systematic Name

English

uprosertib [INN]

Common Name

English

GSK-2141795C

Code

English

UPROSERTIB [USAN]

Common Name

English

Uprosertib [WHO-DD]

Common Name

English

GSK2141795

Code

English

AKT INHIBITOR GSK2141795

Common Name

English

GSK2141795C

Code

English

N-[(1S)-1-(Aminomethyl)-2-(3,4-difluorophenyl)ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-2-carboxamide

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C155764

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

Code System Code Type Description

USAN

AB-111

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

PRIMARY

INN

9942

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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DRUG BANK

DB11969

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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PUBCHEM

51042438

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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ChEMBL

CHEMBL3137336

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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FDA UNII

ZXM835LQ5E

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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CAS

1047634-65-0

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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SMS_ID

100000174861

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

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NCI_THESAURUS

C84870

Created by admin on Sat Dec 16 07:57:11 UTC 2023 , Edited by admin on Sat Dec 16 07:57:11 UTC 2023

PRIMARY

ACTIVE MOIETY


					ZXM835LQ5E

SALT/SOLVATE (PARENT)


					50IE5H22B2

UPROSERTIB HYDROCHLORIDE