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PYRUVATE KINASE PKR
11F03GK3UH
Other
General
Record Details
Names
3
Classification
1
Identifiers
7
Subunits
4
Relationships
3
Characteristic Attributes
2
PYRUVATE KINASE PKR
11F03GK3UH
Other
General
Approval Year
Unknown
86,413
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
11F03GK3UH
Record Status
Validated (UNII)
Record Version
16
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13
12
11
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4
3
2
1
Names
3
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entries
Name
Type
Language
Name
Type
Language
PYRUVATE KINASE PKR
Common Name
English
PYRUVATE KINASE 1
Common Name
English
PYRUVATE KINASE RED BLOOD CELL
Common Name
English
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Classification
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Subpart B--Clinical Chemistry Test Systems
PART 862 -- CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES
Subpart B--Clinical Chemistry Test Systems
Sec. 862.1650 Pyruvate kinase test system.
CFR
21 CFR 862.1650
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Identifiers
7
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Code System
Code
Type
Description
Code System
Code
Type
Description
CAS
625326-52-5
ALTERNATIVE
WIKIPEDIA
PKLR
PRIMARY
EC (ENZYME CLASS)
EC 2.7.1.40
PRIMARY
CAS
479853-13-9
PRIMARY
UNIPROT
P30613
PRIMARY
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Subunits
4
Relationships
3
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Related Record
Type
Details
Related Record
Type
Details
WLI3QP8XYK
PKR-IN-2
ACTIVATOR -> TARGET
Qualification:
EC50
Amount:
[<100] NANOMOLAR (average)
V4E0A9M44Q
ETAVOPIVAT
ACTIVATOR -> TARGET
Comments:
activator to 89% of activity
Qualification:
EC50
Amount:
113 NANOMOLAR (average)
2WTV10SIKH
MITAPIVAT
ACTIVATOR -> TARGET
Comments:
519% activation over baseline
Interaction Type:
ALLOSTERIC
Qualification:
EC50
Amount:
13 NANOMOLAR (average)
ACTIVATOR CONCENTRATION
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)
CHEMICAL
NUMBER AVERAGE 247320 DA (average)
UNMODIFIED MW
Molecular Formula
CHEMICAL
ESTIMATED
C11020H17920N3148O3451P28S76
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