RUTIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H30O16
Molecular Weight	610.5175
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of RUTIN

Structure Search

SMILES

[H][C@@]5(OC[C@H]1O[C@@H](OC2=C(OC3=C(C2=O)C(O)=CC(O)=C3)C4=CC=C(O)C(O)=C4)[C@H](O)[C@@H](O)[C@@H]1O)O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O

InChI

InChIKey=IKGXIBQEEMLURG-NVPNHPEKSA-N

InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H30O16
Molecular Weight	610.5175
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	10 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:02:14 UTC 2023` Edited by `admin` on `Fri Dec 15 15:02:14 UTC 2023`
Record UNII	5G06TVY3R7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RUTIN

Official Name

English

OSYRITRIN

Common Name

English

GLOBULARIACITRIN

Common Name

English

ILIXANTHIN

Common Name

English

RUTIN [MI]

Common Name

English

MYRTICOLORIN

Common Name

English

YUNXIANGGAN

Common Name

English

RUTIN (QUERCETIN-3-O-RUTINOSIDE) (CONSTITUENT OF GINKGO) [DSC]

Common Name

English

RUTIN [INCI]

Common Name

English

QUERCETIN 3-O-.ALPHA.-L-RHAMNOPYRANOSYL-.BETA.-D-GLUCOPYRANOSIDE

Systematic Name

English

TANRUTIN

Common Name

English

QUERCETIN 3-RUTINOSIDE

Common Name

English

RUTIN (QUERCETIN-3-O-RUTINOSIDE) (CONSTITUENT OF HAWTHORN LEAF WITH FLOWER) [DSC]

Common Name

English

VIOLAQUERCETRIN

Common Name

English

NOVARRUTINA

Common Name

English

RUTIN [DSC]

Common Name

English

RUTOSIDE

Official Name

English

C.I. 75730

Code

English

2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-4H-CHROMEN-4-ONE-3-YL 6-O-.ALPHA.-L-RHAMNOPYRANOSYL-.BETA.-D-GLUCOSIDE

Common Name

English

Rutoside [WHO-DD]

Common Name

English

NSC-9220

Code

English

rutoside [INN]

Common Name

English

PALIUROSIDE

Common Name

English

RUTIN [VANDF]

Common Name

English

QUERCETIN-3-O-RUTINOSIDE

Common Name

English

BIRUTAN

Common Name

English

SOPHORIN

Common Name

English

3-RHAMNOGLUCOSIDE OF 5,7,3',4'-TETRAHYDROXYFLAVONOL

Common Name

English

RUTIN [USP-RS]

Common Name

English

Classification Tree Code System Code

DSLD

120 (Number of products:1322)

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

WHO-ATC

C05CA01

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

WHO-VATC

QC05CA01

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

DSLD

1394 (Number of products:104)

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

WHO-VATC

QC05CA51

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

WHO-ATC

C05CA51

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

NCI_THESAURUS

C792

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

Code System Code Type Description

WIKIPEDIA

RUTIN

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

CHEBI

28527

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

SMS_ID

100000090310

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

DRUG CENTRAL

3535

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

CAS

153-18-4

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

DAILYMED

5G06TVY3R7

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

ECHA (EC/EINECS)

205-814-1

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

CHEBI

61606

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

RS_ITEM_NUM

1606503

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

ChEMBL

CHEMBL226335

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

PUBCHEM

5280805

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

EVMPD

SUB10407MIG

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

INN

2213

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

MESH

D012431

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

EPA CompTox

DTXSID3022326

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

MERCK INDEX

m9708

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

Merck Index

FDA UNII

5G06TVY3R7

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

CHEBI

4055

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

DRUG BANK

DB01698

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

NCI_THESAURUS

C819

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

RXCUI

9500

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

RxNorm

NSC

9220

Created by admin on Fri Dec 15 15:02:14 UTC 2023 , Edited by admin on Fri Dec 15 15:02:14 UTC 2023

PRIMARY

Related Record Type Details


					0LMC25OLZY

EUPATORIUM PERFOLIATUM WHOLE

PARENT -> CONSTITUENT ALWAYS PRESENT


					7D3VB244UX

CORN SILK

PARENT -> CONSTITUENT ALWAYS PRESENT


					7114SV0MYK

SELENICEREUS GRANDIFLORUS STEM

PARENT -> CONSTITUENT ALWAYS PRESENT


					GYG64DIH9P

MENYANTHES TRIFOLIATA LEAF

PARENT -> CONSTITUENT ALWAYS PRESENT


					H8M5HO9KR5

CRATAEGUS MONOGYNA FLOWERING TOP

PARENT -> CONSTITUENT ALWAYS PRESENT

Qualification:

USP


					RF4N03853G

RUTOSIDE TRIHYDRATE

SOLVATE->ANHYDROUS


					FGL3685T2X

CHAMOMILE

PARENT -> CONSTITUENT ALWAYS PRESENT


					G55HNL2C70

PARENT -> CONSTITUENT ALWAYS PRESENT


					TKW5C324NM

ETHOXAZORUTOSIDE

SALT/SOLVATE -> PARENT


					RF4N03853G

RUTOSIDE TRIHYDRATE

SALT/SOLVATE -> PARENT


					369DDH39Z0

AGATHOSMA BETULINA LEAF

PARENT -> CONSTITUENT ALWAYS PRESENT


					P0M7O4Y7YD

CALENDULA OFFICINALIS FLOWER

PARENT -> CONSTITUENT ALWAYS PRESENT

Comments:

CALENDULA OFFICINALIS FLOWER flavonoid


					O2T154T6OG

CHAMAEMELUM NOBILE FLOWER

PARENT -> CONSTITUENT ALWAYS PRESENT


					4465L2WS4Y

LONICERA JAPONICA FLOWER

PARENT -> CONSTITUENT ALWAYS PRESENT


					19FUJ2C58T

GINKGO

PARENT -> CONSTITUENT ALWAYS PRESENT

Related Record Type Details


					12GLI7JGB3

4-METHYLCATECHOL

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE


					RY36PD0CQ2

METABOLITE -> PARENT

Comments:

Quantity of quercetin-3-glucuronide in urine of six healthy human subjects 0-24hr (total) after consumption of tomato juice containing 176 micromoles of rutin; Unit: nmoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:


					5MZB5M8D8L

ISORHAMNETIN-3-GLUCURONIDE

METABOLITE -> PARENT

Comments:

Cmax: 4.3 +/- 1.5 nM; Tmax: 5.4 +/- 0.2 hr; T1/2: 6.9 +/- 0.3 hr (n=6)

Interaction Type:

IN-VIVO

Qualification:

PLASMA


					KEX5N0R4N5

3,4-DIHYDROXYPHENYLACETIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

PLASMA; URINE


					9IV9236GRD

3-(3-HYDROXYPHENYL)-3-HYDROXYPROPIONIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE


					5MZB5M8D8L

ISORHAMNETIN-3-GLUCURONIDE

METABOLITE -> PARENT

Comments:

Quantity of Isorhamnetin-3-glucuronide in urine of six healthy human subjects 0-24hr (total) after consumption of tomato juice containing 176 micromoles of rutin; Unit: nmoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:


					RY36PD0CQ2

METABOLITE -> PARENT

Comments:

Cmax: 12 +/- 2 nM; Tmax: 4.7 +/- 0.3 hr; T1/2: 5.7 +/- 0.6 hr (n=6)

Interaction Type:

IN-VIVO

Qualification:

PLASMA


					K59Z6Z8REF

3-HYDROXYBENZENEACETIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE


					K59Z6Z8REF

3-HYDROXYBENZENEACETIC ACID

METABOLITE -> PARENT

Comments:

Excretion of 3-Hydroxyphenylacetic acid in the urine of human subjects (n=6, 0-24hr total) after rutin (176 micromoles) supplemented tomato juice; Unit: micromoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:


					90VNX82LK3

QUERCETIN-4'-GLUCURONIDE

METABOLITE -> PARENT

Comments:

Quantity of Quercetin-4'-glucuronide in urine of five healthy human subjects 0-24hr (total) after consumption of tomato juice containing 176 micromoles of rutin; Unit: nmoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:


					KEX5N0R4N5

3,4-DIHYDROXYPHENYLACETIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE


					KEX5N0R4N5

3,4-DIHYDROXYPHENYLACETIC ACID

METABOLITE -> PARENT

Comments:

Excretion of 3,4-Dihydroxyphenylacetic acid in the urine of human subjects (n=6, 0-24hr total) after rutin (176 micromoles) supplemented tomato juice; Unit: micromoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:


					K59Z6Z8REF

3-HYDROXYBENZENEACETIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

PLASMA; URINE


					X77S6GMS36

HOMOVANILLIC ACID

METABOLITE -> PARENT

Comments:

Excretion of 3-Methoxy-4-Hydroxyphenylacetic acid in the urine of human subjects (n=6, 0-24hr total) after rutin (176 micromoles) supplemented tomato juice; Unit: micromoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:


					X77S6GMS36

HOMOVANILLIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE


					X77S6GMS36

HOMOVANILLIC ACID

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

PLASMA; URINE


					12GLI7JGB3

4-METHYLCATECHOL

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

PLASMA; URINE


					RW0082ZDT2

QUERCETIN-3'-GLUCURONIDE

METABOLITE -> PARENT

Comments:

Quantity of Quercetin-3'-glucuronide in urine of six healthy human subjects 0-24hr (total) after consumption of tomato juice containing 176 micromoles of rutin; Unit: nmoles

Interaction Type:

IN-VIVO

Qualification:

URINE

Amount:

Related Record Type Details


					4056D20K3H

KAEMPFEROL-3-O-RUTINOSIDE

IMPURITY -> PARENT

Comments:

NMT 2%

Qualification:

USP

Amount:


					9IKM0I5T1E

QUERCETIN

IMPURITY -> PARENT

Qualification:

USP


					0YX10VRV6J

IMPURITY -> PARENT

Comments:

NMT 2%

Qualification:

USP

Amount:

Related Record Type Details


					5G06TVY3R7

RUTIN

ACTIVE MOIETY