Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H28N2O3.ClH |
| Molecular Weight | 368.898 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC1=C(O)C(C)=C2CC[C@](C)(OC2=C1C)C(=O)N[C@@H]3CCCNC3
InChI
InChIKey=HVFWCHDZDIRYBZ-MQZJHDQISA-N
InChI=1S/C19H28N2O3.ClH/c1-11-12(2)17-15(13(3)16(11)22)7-8-19(4,24-17)18(23)21-14-6-5-9-20-10-14;/h14,20,22H,5-10H2,1-4H3,(H,21,23);1H/t14-,19+;/m1./s1
| Molecular Formula | C19H28N2O3 |
| Molecular Weight | 332.4372 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:44:43 UTC 2023
by
admin
on
Sat Dec 16 08:44:43 UTC 2023
|
| Record UNII |
858M8246UL
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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EU-Orphan Drug |
EU/3/15/1543
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
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FDA ORPHAN DRUG |
450714
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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EU/3/14/1336(POSITIVE)
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
|
PRIMARY | On 15 October 2014, orphan designation (EU/3/14/1336) was granted by the European Commission to Khondrion BV, the Netherlands, for (S)-6-Hydroxy-2,5,7,8-tetramethyl-N-((R)-piperidin-3‑yl)chroman-2-carboxamide hydrochloride for the treatment of Leigh syndrome. | ||
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EU/3/15/1543(POSITIVE)
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
|
PRIMARY | On 10 August 2015, orphan designation (EU/3/15/1543) was granted by the European Commission to Khondrion BV, the Netherlands, for (S)-6-hydroxy-2,5,7,8-tetramethyl-N-((R)-piperidin-3-yl)chroman-2-carboxamide hydrochloride for the treatment of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes. | ||
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858M8246UL
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
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PRIMARY | |||
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100000180594
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
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PRIMARY | |||
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72710874
Created by
admin on Sat Dec 16 08:44:43 UTC 2023 , Edited by admin on Sat Dec 16 08:44:43 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |