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Details

Stereochemistry RACEMIC
Molecular Formula C7H15Cl2N2O2P.H2O
Molecular Weight 279.101
Optical Activity ( + / - )
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYCLOPHOSPHAMIDE

SMILES

O.ClCCN(CCCl)P1(=O)NCCCO1

InChI

InChIKey=PWOQRKCAHTVFLB-UHFFFAOYSA-N
InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

HIDE SMILES / InChI
Molecular Formula C7H15Cl2N2O2P
Molecular Weight 261.086
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:55:41 UTC 2023
Edited
by admin
on Sat Dec 16 17:55:41 UTC 2023
Record UNII
8N3DW7272P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYCLOPHOSPHAMIDE
EP   ORANGE BOOK   USP   USP-RS   VANDF   WHO-IP  
EP   USP  
Official Name English
(±)-2-(BIS(2-CHLOROETHYL)AMINO)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE MONOHYDRATE
Systematic Name English
CYCLOBLASTIN
Brand Name English
CYCLOPHOSPHAMIDE [MI]
Common Name English
CYCLOPHOSPHAMIDE [WHO-IP]
Common Name English
NSC-756711
Code English
PROCYTOX
Brand Name English
REVIMMUNE
Brand Name English
CYCLOPHOSPHAMIDE [EP MONOGRAPH]
Common Name English
NEOSAR
Brand Name English
CYCLOPHOSPHAMIDUM [WHO-IP LATIN]
Common Name English
CYTOXAN
Brand Name English
ENDOXAN
Brand Name English
CICLOFOSFAMIDE
Common Name English
CYCLOPHOSPHAMIDE [USP-RS]
Common Name English
B-518
Code English
CYTOPHOSPHANE
Common Name English
CYCLOPHOSPHAMIDE [USP MONOGRAPH]
Common Name English
CYCLOPHOSPHANUM [WHO-IP]
Common Name English
ENDOXAN MONOHYDRATE
Common Name English
CYTOPHOSPHAN
Brand Name English
CYCLOPHOSPHAMIDE [VANDF]
Common Name English
2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE, N,N-BIS(2-CHLOROETHYL)TETRAHYDRO-, 2-OXIDE, MONOHYDRATE, (±)-
Common Name English
Cyclophosphamide monohydrate [WHO-DD]
Common Name English
CYCLOSTIN
Brand Name English
CYCLOPHOSPHAMIDE [ORANGE BOOK]
Common Name English
CYCLOPHOSPHAMIDE HYDRATE [JAN]
Common Name English
CYCLOPHOSPHAMIDE MONOHYDRATE
WHO-DD  
Common Name English
CYCLOPHOSPHAMIDE [IARC]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 343611
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
NCI_THESAURUS C697
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
IARC Cyclophosphamide
NDF-RT N0000175558
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
WHO-VATC QL01AA01
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.2
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
FDA ORPHAN DRUG 333711
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
WHO-ATC L01AA01
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
NCI_THESAURUS C574
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
FDA ORPHAN DRUG 333911
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
LIVERTOX NBK548059
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
Code System Code Type Description
RXCUI
3002
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY RxNorm
SMS_ID
100000078558
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
IUPHAR
7154
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
EVMPD
SUB16414MIG
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
CYCLOPHOSPHAMIDE
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY Description: A white, crystalline powder.Solubility: Soluble in water; freely soluble in ethanol (~750 g/l) TS; slightly soluble in ether R.Category: Cytotoxic drug.Storage: Cyclophosphamide should be kept in a tightly closed container and stored at a temperature between 2 and 30 ?C.Additional information. CAUTION: Cyclophosphamide must be handled with care, avoiding contact with the skin and inhalation ofairborne particles.
WIKIPEDIA
CYCLOPHOSPHAMIDE
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
RS_ITEM_NUM
1157002
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
EPA CompTox
DTXSID6024888
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
DRUG BANK
DB00531
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
NSC
756711
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
LACTMED
Cyclophosphamide
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
ChEMBL
CHEMBL88
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
FDA UNII
8N3DW7272P
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
DAILYMED
8N3DW7272P
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
MESH
D003520
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
CHEBI
4026
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
NCI_THESAURUS
C405
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
DRUG CENTRAL
758
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
CAS
6055-19-2
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
PUBCHEM
22420
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
MERCK INDEX
m4013
Created by admin on Sat Dec 16 17:55:42 UTC 2023 , Edited by admin on Sat Dec 16 17:55:42 UTC 2023
PRIMARY
Related Record Type Details
Structure of CYCLOPHOSPHAMIDE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of CYCLOPHOSPHAMIDE ANHYDROUS
PARENT -> SALT/SOLVATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Related Record Type Details
Structure of CHLORODIAZANONYL PHOSPHATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of BIS(2-CHLOROETHYL)AMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of 3-(2-CHLOROETHYL)-2-OXO-2-HYDROXY-1,3,6,2-OXADIAZAPHOSPHONANE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of DIDECHLORODIHYDROXYCYCLOPHOSPHAMIDE
IMPURITY -> PARENT
Structure of AMINOPROPYL DIHYDROGEN PHOSPHATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
USP
Related Record Type Details
Structure of 4-HYDROXYCYCLOPHOSPHAMIDE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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