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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H21N6O7S2.H.5H2O
Molecular Weight 636.652
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CEFTAZIDIME

SMILES

[H+].O.O.O.O.O.[H][C@]12SCC(C[N+]3=CC=CC=C3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C([O-])=O)\C4=CSC(N)=N4)C([O-])=O

InChI

InChIKey=NMVPEQXCMGEDNH-TZVUEUGBSA-N
InChI=1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1

HIDE SMILES / InChI
Molecular Formula H
Molecular Weight 1.0079
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C22H21N6O7S2
Molecular Weight 545.568
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 1
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:15:29 UTC 2023
Edited
by admin
on Fri Dec 15 15:15:29 UTC 2023
Record UNII
9M416Z9QNR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CEFTAZIDIME
DASH   ORANGE BOOK   USAN   USP   VANDF  
USAN  
Official Name English
LY 139381
Code English
CEPTAZ
Brand Name English
LY-139381
Code English
CEFTAZIDIME PENTAHYDRATE
EP   MI   USP-RS   WHO-DD  
Common Name English
CEFTAZIDIME [ORANGE BOOK]
Common Name English
Ceftazidime pentahydrate [WHO-DD]
Common Name English
CEFTAZIDIME HYDRATE [JAN]
Common Name English
CEFTAZIDIME [USAN]
Common Name English
FORTAZ
Brand Name English
PENTACEF
Brand Name English
ZAVICEFTA COMPONENT CEFTAZIDIME
Brand Name English
CEFTAZIDIME PENTAHYDRATE [EP MONOGRAPH]
Common Name English
GR 20263
Code English
1-(((6R,7R)-7-(2-(2-AMINO-4-THIAZOLYL)GLYOXYLAMIDO)-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)PYRIDINIUM HYDROXIDE INNER SALT 7(SUP 2)-(Z)-(O-(1-CARBOXY-1-METHYLETHYL)OXIME), PENTAHYDRATE
Common Name English
CEFTAZIDIME COMPONENT OF ZAVICEFTA
Brand Name English
CEFTAZIDIME COMPONENT OF AVYCAZ
Brand Name English
CEFTAZIDIME PENTAHYDRATE [MI]
Common Name English
TAZIDIME
Brand Name English
AVYCAZ COMPONENT CEFTAZIDIME
Brand Name English
TAZICEF
Brand Name English
CEFTAZIDIME PENTAHYDRATE [USP-RS]
Common Name English
J01DD07
Code English
CEFTAZIDIME [VANDF]
Common Name English
CEFTAZIDIME [USP MONOGRAPH]
Common Name English
GR-20263
Code English
PYRIDINIUM, 1-((7-(((2-AMINO-4-THIAZOLYL)((1-CARBOXY-1-METHYLETHOXY)IMINO)ACETYL)AMINO)-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)-, HYDROXIDE, INNER SALT, PENTAHYDRATE, (6R-(6.ALPHA.,7.BETA.(Z)))-
Common Name English
Classification Tree Code System Code
WHO-ESSENTIAL MEDICINES LIST 6.2.1
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
WHO-VATC QJ01DD02
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
NDF-RT N0000175488
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
LIVERTOX NBK548666
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
WHO-ATC J01DD52
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
WHO-ATC J01DD02
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
LIVERTOX NBK547862
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
NCI_THESAURUS C357
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
Code System Code Type Description
RS_ITEM_NUM
1098130
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
SMS_ID
100000084683
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
USAN
R-101
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
EVMPD
SUB01134MIG
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
CHEBI
3509
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
MESH
D002442
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
LACTMED
Ceftazidime
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
CAS
78439-06-2
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
RXCUI
235552
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
NCI_THESAURUS
C66868
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
EPA CompTox
DTXSID0045599
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
WIKIPEDIA
CEFTAZIDIME
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
CHEBI
3508
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
MERCK INDEX
m3218
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY Merck Index
RXCUI
2191
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
ALTERNATIVE
DAILYMED
9M416Z9QNR
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
PUBCHEM
6536864
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
LACTMED
Ceftazidime and Avibactam
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
DRUG BANK
DB00438
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
ChEMBL
CHEMBL44354
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
FDA UNII
9M416Z9QNR
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
DRUG CENTRAL
559
Created by admin on Fri Dec 15 15:15:29 UTC 2023 , Edited by admin on Fri Dec 15 15:15:29 UTC 2023
PRIMARY
Related Record Type Details
Structure of CEFTAZIDIME ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
Structure of CEFTAZIDIME ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of CEFTAZIDIME ANHYDROUS
ANHYDROUS->SOLVATE
Structure of CEFTAZIDIME ANHYDROUS
PARENT -> SALT/SOLVATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Related Record Type Details
Structure of CEFTAZIDIME ANHYDROUS, (E)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-oxo-2-[(2-oxoethyl)amino]ethylidene]amino]oxy]-2-methylpropanoic acid
IMPURITY -> PARENT
For the calculation of content, multiply the peak area of by 3.0
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PYRIDINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of CEFTAZIDIME ANHYDROUS
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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