NEVIRAPINE HEMIHYDRATE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C15H14N4O.H2O
Molecular Weight	550.611
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NEVIRAPINE HEMIHYDRATE

Structure Search

SMILES

O.CC1=CC=NC2=C1NC(=O)C3=C(N=CC=C3)N2C4CC4.CC5=CC=NC6=C5NC(=O)C7=C(N=CC=C7)N6C8CC8

InChI

InChIKey=KMTLSXAXTLQBKJ-UHFFFAOYSA-N

InChI=1S/2C15H14N4O.H2O/c2*1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10;/h2*2-3,6-8,10H,4-5H2,1H3,(H,18,20);1H2

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C15H14N4O
Molecular Weight	266.2979
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 21:18:13 UTC 2023` Edited by `admin` on `Fri Dec 15 21:18:13 UTC 2023`
Record UNII	B7XF2TD73C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NEVIRAPINE HEMIHYDRATE

Common Name

English

NEVIRAPINE HEMIHYDRATE [WHO-IP]

Common Name

English

NEVIRAPINE HEMIHYDRATE [EP MONOGRAPH]

Common Name

English

Nevirapine hemihydrate [WHO-DD]

Common Name

English

NEVIRAPINE HEMIHYDRATE [USP-RS]

Common Name

English

NEVIRAPINUM HEMIHYDRATE [WHO-IP LATIN]

Common Name

English

NEVIRAPINE HEMIHYDRATE [USP MONOGRAPH]

Common Name

English

6H-DIPYRIDO(3,2-B:2',3'-E)(1,4)DIAZEPIN-6-ONE, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-, HYDRATE (2:1)

Systematic Name

English

Code System Code Type Description

RS_ITEM_NUM

1460714

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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DRUG BANK

DBSALT002723

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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SMS_ID

100000127941

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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WHO INTERNATIONAL PHARMACOPEIA

NEVIRAPINE HEMIHYDRATE

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

PRIMARY

Description: A white to almost white powder. Solubility: Practically insoluble in water, sparingly to slightly soluble in dichloromethane R, slightly soluble in methanol R. Category: Antiretroviral (Non-Nucleoside Reverse Transcriptase Inhibitor). Storage: Nevirapine should be kept in a well-closed container. Labelling: The designation on the container should state whether the substance is the hemihydrate or is in the anhydrous form. Definition: Nevirapine contains not less than 98.0% and not more than 102.0% of nevirapine (C15H14N4O), calculated with reference to the anhydrous substance.

PUBCHEM

9959243

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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RXCUI

2462459

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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EPA CompTox

DTXSID30176606

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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DAILYMED

B7XF2TD73C

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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FDA UNII

B7XF2TD73C

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

PRIMARY

EVMPD

SUB34149

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

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CAS

220988-26-1

Created by admin on Fri Dec 15 21:18:13 UTC 2023 , Edited by admin on Fri Dec 15 21:18:13 UTC 2023

PRIMARY

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Amount:


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ACTIVE MOIETY