ARTEMETHER

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H26O5
Molecular Weight	298.3746
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ARTEMETHER

Structure Search

SMILES

[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@]4(C)OO[C@@]13[C@]([H])(O[C@H](OC)[C@@H]2C)O4

InChI

InChIKey=SXYIRMFQILZOAM-HVNFFKDJSA-N

InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C16H26O5
Molecular Weight	298.3746
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:12 UTC 2023` Edited by `admin` on `Fri Dec 15 15:40:12 UTC 2023`
Record UNII	C7D6T3H22J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ARTEMETHER

Official Name

English

.BETA.-ARTEMETHER

Common Name

English

NSC-665970

Code

English

GVITHER

Common Name

English

(+)-ARTEMETHER

Common Name

English

ARTEMETHER [JAN]

Common Name

English

COARTEM COMPONENT ARTEMETHER

Brand Name

English

SM224

Code

English

ARTEMETHER [MART.]

Common Name

English

(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j]-1,2-benzodioxepine

Common Name

English

ARTEMETHERUM [WHO-IP LATIN]

Common Name

English

MALARTEM

Common Name

English

NSC-759820

Code

English

(3R,5AS,6R,8AS,9R,10S,12R,12AR)-DECAHYDRO-10-METHOXY-3,6,9-TRIMETHYL-3,12-EPOXY-12H-PYRANO(4,3-J)-1,2-BENZODIOXEPIN

Systematic Name

English

ARTEMETHER [HSDB]

Common Name

English

ARTESAPH

Common Name

English

LARITHER

Common Name

English

ARTEMETHER [USAN]

Common Name

English

FALCIDOL

Common Name

English

PALUTHER

Common Name

English

3,12-EPOXY-12H-PYRANO(4,3-J)-1,2-BENZODIOXEPIN, DECAHYDRO-10-METHOXY-3,6,9-TRIMETHYL-, (3R,5AS,6R,8AS,9R,10S,12R,12AR)-

Common Name

English

ARTEMETHER [USP-RS]

Common Name

English

Artemether [WHO-DD]

Common Name

English

artemether [INN]

Common Name

English

.BETA.-DIHYDROARTEMISININ METHYL ETHER

Common Name

English

ARTEMETHER [MI]

Common Name

English

ARTEMETHER [VANDF]

Common Name

English

ARTEMETHER [WHO-IP]

Common Name

English

ARTEMETHER COMPONENT OF COARTEM

Brand Name

English

ARTEMETHER [ORANGE BOOK]

Common Name

English

Classification Tree Code System Code

WHO-ATC

P01BF01

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.5.3.1

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

NDF-RT

N0000175482

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

FDA ORPHAN DRUG

245507

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

WHO-ATC

P01BE02

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.5.3.1 (ART/LUM)

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

EU-Orphan Drug

EU/3/09/702

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

NCI_THESAURUS

C271

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

Code System Code Type Description

FDA UNII

C7D6T3H22J

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

WIKIPEDIA

ARTEMETHER

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

PUBCHEM

68911

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

ChEMBL

CHEMBL566534

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

MESH

C032942

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

NSC

665970

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

RXCUI

18343

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

RxNorm

LACTMED

Artemether and Lumefantrine

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

EVMPD

SUB05574MIG

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

CHEBI

195280

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

DAILYMED

C7D6T3H22J

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

RS_ITEM_NUM

1042780

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

MERCK INDEX

m2075

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

Merck Index

NCI_THESAURUS

C73001

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

EPA CompTox

DTXSID7040651

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

DRUG BANK

DB06697

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

HSDB

7456

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

ARTEMETHER

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

Description: White crystals or a white, crystalline powder. Solubility: Practically insoluble in water; very soluble in dichloromethane R and acetone R; freely soluble in ethyl acetate R and dehydrated ethanol R. Category: Antimalarial drug. Storage: Artemether should be kept in a tightly closed container and protected from light. Labelling: The designation Artemether for parenteral use indicates that the substance complies with the additional requirements and may be used for parenteral administration. Additional information: The parenteral form is normally intended for intramuscular administration. Requirement: Artemether contains not less than 97.0% and not more than the equivalent of 102.0% of C16H26O5 using ?Assay?, method A, andnot less than 98.0% and not more than the equivalent of 102.0% of C16H26O5 using ?Assay?, method B, both calculated with reference to the dried substance.

NSC

759820

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

USAN

UU-173

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

INN

6458

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

SMS_ID

100000092762

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

DRUG CENTRAL

245

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

CAS

71963-77-4

Created by admin on Fri Dec 15 15:40:12 UTC 2023 , Edited by admin on Fri Dec 15 15:40:12 UTC 2023

PRIMARY

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ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC