U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula 2C30H53N3O6.C4H4O4
Molecular Weight 1219.5888
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ALISKIREN HEMIFUMARATE

SMILES

OC(=O)\C=C\C(O)=O.COCCCOC1=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=CC=C1OC.COCCCOC2=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=CC=C2OC

InChI

InChIKey=KLRSDBSKUSSCGU-KRQUFFFQSA-N
InChI=1S/2C30H53N3O6.C4H4O4/c2*1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36;5-3(6)1-2-4(7)8/h2*10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35);1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*22-,23-,24-,25-;/m00./s1

HIDE SMILES / InChI
Molecular Formula C4H4O4
Molecular Weight 116.0722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE
Molecular Formula C30H53N3O6
Molecular Weight 551.7583
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:55:51 UTC 2023
Edited
by admin
on Fri Dec 15 15:55:51 UTC 2023
Record UNII
C8A0P8G029
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALISKIREN HEMIFUMARATE
MI   ORANGE BOOK   VANDF  
Common Name English
SPRIMEO-HCT COMPONENT ALISKIREN HEMIFUMARATE
Brand Name English
AMTURNIDE COMPONENT ALISKIREN HEMIFUMARATE
Common Name English
ALISKIREN HEMIFUMARATE [MI]
Common Name English
TEKTURNA HCT COMPONENT ALISKIREN HEMIFUMARATE
Common Name English
RASILAMLO COMPONENT ALISKIREN HEMIFUMARATE
Brand Name English
Aliskiren Fumarate [WHO-DD]
Common Name English
TEKAMLO COMPONENT ALISKIREN HEMIFUMARATE
Common Name English
ALISKIREN HEMIFUMARATE COMPONENT OF RASITRIO
Brand Name English
ALISKIREN HEMIFUMARATE COMPONENT OF AMTURNIDE
Common Name English
ENVIAGE
Brand Name English
ALISKIREN FUMARATE
JAN   MART.   USAN   WHO-DD  
USAN  
Official Name English
VALTURNA COMPONENT ALISKIREN HEMIFUMARATE
Brand Name English
RAPRAZO-HCT COMPONENT ALISKIREN HEMIFUMARATE
Brand Name English
ALISKIREN HEMIFUMARATE COMPONENT OF VALTURNA
Brand Name English
ALISKIREN HEMIFUMARATE [ORANGE BOOK]
Common Name English
RASILEZ
Brand Name English
RASILEZ-HCT COMPONENT ALISKIREN HEMIFUMARATE
Brand Name English
ALISKIREN HEMIFUMARATE COMPONENT OF RASILAMLO
Brand Name English
RASITRIO COMPONENT ALISKIREN HEMIFUMARATE
Brand Name English
ALISKIREN HEMIFUMARATE COMPONENT OF TEKAMLO
Common Name English
NSC-759185
Code English
ALISKIREN HEMIFUMARATE COMPONENT OF SPRIMEO-HCT
Brand Name English
ALISKIREN FUMARATE [USAN]
Common Name English
ALISKIREN HEMIFUMARATE COMPONENT OF RASILEZ-HCT
Brand Name English
Bis(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methyl-2-(1-methylethyl)nonanamide] (2E)-but-2-enedioate
Common Name English
ALISKIREN FUMARATE [MART.]
Common Name English
RIPRAZO
Brand Name English
TEKTURNA
Brand Name English
SPP-100B
Code English
SPRIMEO
Brand Name English
ALISKIREN HEMIFUMARATE COMPONENT OF TEKTURNA HCT
Common Name English
ALISKIREN FUMARATE [JAN]
Common Name English
ALISKIREN HEMIFUMARATE [VANDF]
Common Name English
ALISKIREN HEMIFUMARATE COMPONENT OF RAPRAZO-HCT
Brand Name English
ALISKIREN (AS FUMARATE)
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS RIPRAZO (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS RASILAMLO (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS TEKTURNA (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS RASILEZ-HCT (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS SPRIMEO (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS RASILEZ (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
NCI_THESAURUS C270
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS SPRIMEO-HCT (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS ENVIAGE (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS RIPRAZO-HCT (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
EMA ASSESSMENT REPORTS RASITRIO (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID601026205
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
PUBCHEM
6918427
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
NSC
759185
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
JAPANESE REVIEW
RASILEZ
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY APPROVED JULY 2009
DAILYMED
C8A0P8G029
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
SMS_ID
100000089500
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
NCI_THESAURUS
C65223
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
MESH
C446481
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
EVMPD
SUB25474
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
CHEBI
53777
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
FDA UNII
C8A0P8G029
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
MERCK INDEX
m1509
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY Merck Index
DRUG BANK
DBSALT001203
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
CAS
173334-58-2
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
RXCUI
732498
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY RxNorm
ChEMBL
CHEMBL1639
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
USAN
RR-96
Created by admin on Fri Dec 15 15:55:51 UTC 2023 , Edited by admin on Fri Dec 15 15:55:51 UTC 2023
PRIMARY
Related Record Type Details
Structure of ALISKIREN
PARENT -> SALT/SOLVATE
Structure of Fumaric acid
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of ALISKIREN
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966