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Details

Stereochemistry ABSOLUTE
Molecular Formula C11H12N2S.ClH
Molecular Weight 240.752
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEVAMISOLE HYDROCHLORIDE

SMILES

Cl.C1CN2C[C@@H](N=C2S1)C3=CC=CC=C3

InChI

InChIKey=LAZPBGZRMVRFKY-HNCPQSOCSA-N
InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C11H12N2S
Molecular Weight 204.291
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:25:20 UTC 2023
Edited
by admin
on Fri Dec 15 15:25:20 UTC 2023
Record UNII
DL9055K809
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEVAMISOLE HYDROCHLORIDE
EP   GREEN BOOK   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   WHO-DD   WHO-IP  
USAN  
Official Name English
LEVAMISOLE HYDROCHLORIDE [EP MONOGRAPH]
Common Name English
LEVAMISOLE HYDROCHLORIDE [MART.]
Common Name English
R-12564
Code English
LEVAMISOLE HYDROCHLORIDE [USP-RS]
Common Name English
LEVAMISOLE HYDROCHLORIDE [MI]
Common Name English
LEVAMISOLE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
LEVAMISOLI HYDROCHLORIDUM [WHO-IP LATIN]
Common Name English
LEVAMISOLE HYDROCHLORIDE [JAN]
Common Name English
IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-PHENYL-, MONOHYDROCHLORIDE, (S)-
Common Name English
SPARTAKON L
Common Name English
TETRAMISOLE HYDROCHLORIDE, (S)-
Common Name English
LEVAMISOLE HYDROCHLORIDE [WHO-IP]
Common Name English
LEVAMISOLE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
(-)-2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO(2,1-B)THIAZOLE MONOHYDROCHLORIDE
Systematic Name English
Levamisole hydrochloride [WHO-DD]
Common Name English
ERGAMISOL
Brand Name English
LEVAMISOLE HYDROCHLORIDE [USAN]
Common Name English
L-NARPENOL
Common Name English
LEVAMISOLE HYDROCHLORIDE [GREEN BOOK]
Common Name English
R 12654
Code English
LEVAMISOLE HCL
Common Name English
R 12,564
Code English
NSC-177023
Code English
ASCARIDIL
Common Name English
Classification Tree Code System Code
EU-Orphan Drug EU/3/05/324
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
CFR 21 CFR 520.1242E
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
NCI_THESAURUS C2141
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
CFR 21 CFR 556.350
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
Code System Code Type Description
CAS
16595-80-5
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
DRUG BANK
DBSALT000822
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
NCI_THESAURUS
C610
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
LEVAMISOLE HYDROCHLORIDE
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder. Solubility: Freely soluble in water; soluble in ethanol (~750 g/L) TS; slightly soluble in dichloromethane R. Category: Anthelminthic. Storage: Levamisole hydrochloride should be kept in a well-closed container, protected from light. Requirement: Levamisole hydrochloride contains not less than 98.5% and not more than 101.0% of C11H12N2S,HCl, calculated with reference to the dried substance.
EPA CompTox
DTXSID7047518
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
ChEMBL
CHEMBL1454
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
NSC
177023
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
FDA UNII
DL9055K809
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
DAILYMED
DL9055K809
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
RS_ITEM_NUM
1359302
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
PUBCHEM
27944
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
EVMPD
SUB02902MIG
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
MERCK INDEX
m6781
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY Merck Index
RXCUI
227227
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY RxNorm
SMS_ID
100000088106
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
ECHA (EC/EINECS)
240-654-6
Created by admin on Fri Dec 15 15:25:20 UTC 2023 , Edited by admin on Fri Dec 15 15:25:20 UTC 2023
PRIMARY
Related Record Type Details
Structure of TETRAMISOLE HYDROCHLORIDE
RACEMATE -> ENANTIOMER
Structure of LEVAMISOLE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of 3-(.BETA.-AMINOPHENETHYL)-2-THIAZOLIDINONE
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 2.0
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 6-PHENYL-2,3-DIHYDROIMIDAZO(2,1-B)THIAZOLE
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 1.3
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-THIAZOLIDINIMINE, 3-(2-PHENYLETHENYL)-, (E)-
IMPURITY -> PARENT
Levamisole hydrochloride Impurity B. The chromatogram obtained with solution (1) may show peaks due to the following impurities eluting at the following relative retention with reference to levamisole (retention time about 3.5 minutes): impurity B about 1.4. In the chromatogram obtained with solution (1):?the area of any peak corresponding to impurity B, when multiplied by a correction factor of 1.7, is not greater than 2 times the area of the peak due to levamisole in the chromatogram obtained with solution (4) (0.2%).
Structure of 2-THIAZOLIDINIMINE, 3-(2-PHENYLETHENYL)-, (E)-
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 1.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-(.BETA.-AMINOPHENETHYL)-2-THIAZOLIDINONE
IMPURITY -> PARENT
Levamisole hydrochloride Impurity A. The chromatogram obtained with solution (1) may show peaks due to the following impurities eluting at the following relative retention with reference to levamisole (retention time about 3.5 minutes): impurity A about 0.9. In the chromatogram obtained with solution (1):?the area of any peak corresponding to impurity A, when multiplied by a correction factor of 2.0, is not greater than 2 times the area of the peak due to levamisole in the chromatogram obtained with solution (4) (0.2%).
Structure of 2-OXO-3-(2-MERCAPTOETHYL)-5-PHENYLIMIDAZOLIDINE, (±)-
IMPURITY -> PARENT
Levamisole hydrochloride Impurity C. The chromatogram obtained with solution (1) may show peaks due to the following impurities eluting at the following relative retention with reference to levamisole (retention time about 3.5 minutes): impurity C about 1.5. In the chromatogram obtained with solution (1):?the area of any peak corresponding to impurity C, when multiplied by a correction factor of 2.9, is not greater than 2 times the area of the peak due to levamisole in the chromatogram obtained with solution (4) (0.2%).
Structure of BIS(2-(2-OXO-4-PHENYLIMIDAZOLIDIN-1-YL)ETHYL) DISULFIDE
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 2.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-OXO-3-(2-MERCAPTOETHYL)-5-PHENYLIMIDAZOLIDINE, (±)-
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 2.9
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 6-PHENYL-2,3-DIHYDROIMIDAZO(2,1-B)THIAZOLE
IMPURITY -> PARENT
Levamisole hydrochloride Impurity D. The chromatogram obtained with solution (1) may show peaks due to the following impurities eluting at the following relative retention with reference to levamisole (retention time about 3.5 minutes): impurity D about 1.6. In the chromatogram obtained with solution (1):?the area of any peak corresponding to impurity D, when multiplied by a correction factor of 1.3, is not greater than 2 times the area of the peak due to levamisole in the chromatogram obtained with solution (4) (0.2%).
Structure of BIS(2-(2-OXO-4-PHENYLIMIDAZOLIDIN-1-YL)ETHYL) DISULFIDE
IMPURITY -> PARENT
Levamisole hydrochloride Impurity E. The chromatogram obtained with solution (1) may show peaks due to the following impurities eluting at the following relative retention with reference to levamisole (retention time about 3.5 minutes): impurity E about 2.0. In the chromatogram obtained with solution (1):?the area of any peak corresponding to impurity E, when multiplied by a correction factor of 2.7, is not greater than 2 times the area of the peak due to levamisole in the chromatogram obtained with solution (4) (0.2%).
Related Record Type Details
Structure of LEVAMISOLE
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