RUBITECAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H15N3O6
Molecular Weight	393.3496
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of RUBITECAN

Structure Search

SMILES

CC[C@@]1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=C(C5=C4)[N+]([O-])=O)C2=O

InChI

InChIKey=VHXNKPBCCMUMSW-FQEVSTJZSA-N

InChI=1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H15N3O6
Molecular Weight	393.3496
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:59:22 UTC 2023` Edited by `admin` on `Sat Dec 16 15:59:22 UTC 2023`
Record UNII	H19C446XXB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RUBITECAN

Official Name

English

9-NITRO-20-(S)-CAMPTOTHECIN

Common Name

English

9-NC

Common Name

English

rubitecan [INN]

Common Name

English

RFS2000

Code

English

Rubitecan [WHO-DD]

Common Name

English

RFS-2000

Code

English

RUBITECAN [USAN]

Common Name

English

1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4-ETHYL-4-HYDROXY-10-NITRO-, (4S)-

Systematic Name

English

RUBITECAN [MI]

Common Name

English

RUBITECAN [MART.]

Common Name

English

9-NITRO-20(S)-CAMPTOTHECIN

Common Name

English

9-Nitrocamptothecin

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

100196

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

FDA ORPHAN DRUG

142201

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

EU-Orphan Drug

EU/3/03/145

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

NCI_THESAURUS

C2843

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

FDA ORPHAN DRUG

156602

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

Code System Code Type Description

FDA UNII

H19C446XXB

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

MERCK INDEX

m9691

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

Merck Index

CAS

91421-42-0

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

NCI_THESAURUS

C1485

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

EVMPD

SUB33089

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

EPA CompTox

DTXSID7046752

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

INN

7946

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

CHEBI

90225

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

DRUG BANK

DB06159

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

ChEMBL

CHEMBL77305

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

USAN

LL-40

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

DRUG CENTRAL

2411

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

WIKIPEDIA

RUBITECAN

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

PUBCHEM

472335

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

SMS_ID

100000126103

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

MESH

C079905

Created by admin on Sat Dec 16 15:59:23 UTC 2023 , Edited by admin on Sat Dec 16 15:59:23 UTC 2023

PRIMARY

Related Record Type Details


					5MB77ICE2Q

9-AMINOCAMPTOTHECIN

METABOLITE ACTIVE -> PRODRUG

Amount:

Related Record Type Details


					5MB77ICE2Q

9-AMINOCAMPTOTHECIN

ACTIVE MOIETY

Amount: