Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H20O4 |
| Molecular Weight | 324.3704 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1(C)OC2=C(C=C1)C3=C(C[C@@H](CO3)C4=CC=C(O)C=C4O)C=C2
InChI
InChIKey=LBQIJVLKGVZRIW-ZDUSSCGKSA-N
InChI=1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m0/s1
| Molecular Formula | C20H20O4 |
| Molecular Weight | 324.3704 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 20:17:42 UTC 2023
by
admin
on
Fri Dec 15 20:17:42 UTC 2023
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| Record UNII |
HOC5567T41
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C306
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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| Code System | Code | Type | Description | ||
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C107601
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DTXSID00208589
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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HOC5567T41
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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GLABRIDIN
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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HOC5567T41
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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59870-68-7
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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C64171
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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124052
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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1603522
Created by
admin on Fri Dec 15 20:17:42 UTC 2023 , Edited by admin on Fri Dec 15 20:17:42 UTC 2023
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PRIMARY | RxNorm |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Minimum Inhibitory Concentration(MIC) for Staphylococcus aureus (ATCC 13709) = 6.25 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 6.25 mcg ml.
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DERIVATIVE -> PARENT |
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PARENT -> CONSTITUENT ALWAYS PRESENT |
GLABRIDIN exhibited antimicrobial activity (MICs 3.13?12.5 ug/ml) against MSSAs (strains FDA 209P and Smith) and MRSAs(strains K3 and ST 28).
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PARENT -> CONSTITUENT ALWAYS PRESENT |
0.11% of dry weight of contents.
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Anti-HCV activity IC50 was found to be be 6.2 ug/mL.
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Among the chemical constituents of the plant, glabridin and glabrene exhibit inhibitory activity against the growth of Helicobacter pylori in vitro. These flavonoids also showed anti-H. pylori activity against a clarithromycin and amoxicillin resistant strain (Fukai et al. 2002).
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