CARBIDOPA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H14N2O4.H2O
Molecular Weight	244.2444
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CARBIDOPA

Structure Search

SMILES

O.C[C@@](CC1=CC(O)=C(O)C=C1)(NN)C(O)=O

InChI

InChIKey=QTAOMKOIBXZKND-PPHPATTJSA-N

InChI=1S/C10H14N2O4.H2O/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4,12-14H,5,11H2,1H3,(H,15,16);1H2/t10-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H14N2O4
Molecular Weight	226.2292
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:14:20 UTC 2023` Edited by `admin` on `Fri Dec 15 15:14:20 UTC 2023`
Record UNII	MNX7R8C5VO
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CARBIDOPA

Official Name

English

Carbidopa monohydrate [WHO-DD]

Common Name

English

(-)-L-.ALPHA.-HYDRAZINO-3,4-DIHYDROXY-.ALPHA.-METHYLHYDROCINNAMIC ACID MONOHYDRATE

Common Name

English

CARBIDOPA COMPONENT OF PARCOPA

Common Name

English

CARBIDOPA [MI]

Common Name

English

CARBIDOPA [USP MONOGRAPH]

Common Name

English

CARBIDOPA [EMA EPAR]

Common Name

English

CARBIDOPA [USP-RS]

Common Name

English

MK-486

Code

English

CARBIDOPA HYDRATE [JAN]

Common Name

English

CARBIDOPUM MONOHYDRATE [WHO-IP LATIN]

Common Name

English

DUOPA COMPONENT CARBIDOPA

Brand Name

English

STALEVO COMPONENT CARBIDOPA

Brand Name

English

CORBILTA COMPONENT CARBIDOPA

Brand Name

English

CARBIDOPA [VANDF]

Common Name

English

NSC-751137

Code

English

CARBIDOPA COMPONENT OF STALEVO

Brand Name

English

CARBIDOPA COMPONENT OF DOPASNAP

Common Name

English

RYTARY COMPONENT CARBIDOPA

Brand Name

English

DOPASNAP COMPONENT CARBIDOPA

Common Name

English

DHIVY COMPONENT CARBIDOPA

Brand Name

English

CARBIDOPA [ORANGE BOOK]

Common Name

English

CARBIDOPA COMPONENT OF CARBILEV

Common Name

English

CARBIDOPA COMPONENT OF DHIVY

Brand Name

English

CARBIDOPA [EP MONOGRAPH]

Common Name

English

CARBIDOPA COMPONENT OF DUOPA

Brand Name

English

CARBILEV COMPONENT CARBIDOPA

Common Name

English

NSC-758190

Code

English

BENZENEPROPANOIC ACID, .ALPHA.-HYDRAZINO-3,4-DIHYDROXY-.ALPHA.-METHYL-, MONOHYDRATE, (S)-

Common Name

English

IPX-203 COMPONENT CARBIDOPA

Common Name

English

CARBIDOPA COMPONENT OF LEVODOPA/CARBIDOPA/ENTACAPONE ORION

Brand Name

English

CARBIDOPA COMPONENT OF SINEMET

Common Name

English

CARBIDOPA COMPONENT OF RYTARY

Brand Name

English

LODOSYN

Brand Name

English

PARCOPA COMPONENT CARBIDOPA

Common Name

English

CARBIDOPA MONOHYDRATE [WHO-IP]

Common Name

English

LEVODOPA/CARBIDOPA/ENTACAPONE ORION COMPONENT CARBIDOPA

Brand Name

English

CARBIDOPA COMPONENT OF CORBILTA

Brand Name

English

SINEMET COMPONENT CARBIDOPA

Common Name

English

CARBIDOPA MONOHYDRATE

Common Name

English

CARBIDOPA [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66884

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

LIVERTOX

NBK548734

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

NCI_THESAURUS

C38149

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

NDF-RT

N0000175755

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

EMA ASSESSMENT REPORTS

CORBILTA (AUTHORIZED: NERVOUS SYSTEM DISEASES)

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

EMA ASSESSMENT REPORTS

STALEVO (AUTHORIZED: PARKINSON DIEASE)

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

09 (LEV/CAR)

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

EMA ASSESSMENT REPORTS

CORBILTA (AUTHORIZED: PARKINSON DISEASE)

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

EMA ASSESSMENT REPORTS

LEVODOPA/CARBIDOPA/ENTACAPONE ORION (AUTHORIZED: PARKINSON DISEASE)

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

NDF-RT

N0000175754

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

WHO-ATC

N04BA05

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

FDA ORPHAN DRUG

129499

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

Code System Code Type Description

EVMPD

SUB21619

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

EPA CompTox

DTXSID50904589

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

CHEBI

3395

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

FDA UNII

MNX7R8C5VO

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

MESH

D002230

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

PUBCHEM

38101

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

RS_ITEM_NUM

1095506

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

CAS

38821-49-7

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

IUPHAR

5159

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

DRUG CENTRAL

496

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

NCI_THESAURUS

C47431

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

DAILYMED

MNX7R8C5VO

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

MERCK INDEX

m3068

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

CARBIDOPA

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

DRUG BANK

DB00190

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

CARBIDOPA

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

Description: A white to creamy white powder; odourless or almost odourless. Solubility: Slightly soluble in water; very slightly soluble in ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Antiparkinsonism drug. Storage: Carbidopa should be kept in a well-closed container, protected from light. Definition: Carbidopa contains not less than 99.0% and not more than 101.0% of C10H14N2O4, calculated with reference to the anhydrous substance.

RXCUI

2019

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

RxNorm

ChEMBL

CHEMBL1201236

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

NSC

758190

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

NSC

751137

Created by admin on Fri Dec 15 15:14:20 UTC 2023 , Edited by admin on Fri Dec 15 15:14:20 UTC 2023

PRIMARY

Related Record Type Details


					KR87B45RGH

CARBIDOPA ANHYDROUS

PARENT -> SALT/SOLVATE


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					KR87B45RGH

CARBIDOPA ANHYDROUS

ANHYDROUS->SOLVATE


					BY6OQ7Q6TP

AROMATIC-L-AMINO-ACID DECARBOXYLASE

TARGET -> INHIBITOR

Related Record Type Details


					4161KA24ZB

3,4-DIHYDROXYPHENYLACETONE

IMPURITY -> PARENT

Amount:


					49ARC1V0F1

.ALPHA.-METHYL-MELEVODOPA

IMPURITY -> PARENT

Amount:


					O8O4Q22L14

3-O-METHYLCARBIDOPA

IMPURITY -> PARENT

Amount:


					0O6NJX3L6R

2-Bromo (S)-Carbidopa

IMPURITY -> PARENT

Amount:


					M4R0H12F6M

METHYLDOPA ANHYDROUS

IMPURITY -> PARENT

Amount:


					SQ4GVM60UJ

CARBIDOPA ETHYL ESTER

IMPURITY -> PARENT

Amount:


					VFC2H8CA32

(2S)-3-(3-BROMO-4,5-DIHYDROXYPHENYL)-2-HYDRAZINO-2-METHYLPROPANOIC ACID

IMPURITY -> PARENT

Amount:


					EMD84YC5BF

4-O-METHYL CARBIDOPA

IMPURITY -> PARENT

Amount:


					MW9T4Q8H25

3,4-O,O-DIMETHYL CARBIDOPA

IMPURITY -> PARENT

Amount:


					EJ24A8QHH9

BENZENEPROPANOIC ACID, .ALPHA.-HYDRAZINO-3,4-DIHYDROXY-.ALPHA.-METHYL-, METHYL ESTER, (S)-

IMPURITY -> PARENT

Amount:


					A66PDY34A3

CARBIDOPA HYDANTOIC ACID

IMPURITY -> PARENT

Amount:


					97OQQ9E86L

.ALPHA.-(2-CYCLOHEXYLIDENEHYDRAZINYL)-CARBIDOPA METHYL

IMPURITY -> PARENT

Amount:

Related Record Type Details


					KR87B45RGH

CARBIDOPA ANHYDROUS

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC