Cabozantinib Hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H24FN3O5.ClH
Molecular Weight	537.967
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3)=CC=NC2=C1

InChI

InChIKey=LCNVAOXPKXBXEH-UHFFFAOYSA-N

InChI=1S/C28H24FN3O5.ClH/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18;/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34);1H

HIDE SMILES / InChI

Molecular Formula	C28H24FN3O5
Molecular Weight	501.5057
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:53:49 UTC 2023` Edited by `admin` on `Sat Dec 16 19:53:49 UTC 2023`
Record UNII	NQ78NA4UAX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cabozantinib Hydrochloride

Common Name

English

Cabozantinib hydrochloride (1:1)

Common Name

English

N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide hydrochloride

Systematic Name

English

1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N′-(4-fluorophenyl)-, hydrochloride (1:1)

Systematic Name

English

Code System Code Type Description

FDA UNII

NQ78NA4UAX

Created by admin on Sat Dec 16 19:53:49 UTC 2023 , Edited by admin on Sat Dec 16 19:53:49 UTC 2023

PRIMARY

PUBCHEM

122573030

Created by admin on Sat Dec 16 19:53:49 UTC 2023 , Edited by admin on Sat Dec 16 19:53:49 UTC 2023

PRIMARY

CAS

1817759-42-4

Created by admin on Sat Dec 16 19:53:49 UTC 2023 , Edited by admin on Sat Dec 16 19:53:49 UTC 2023

PRIMARY

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Amount:

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ACTIVE MOIETY

Amount:

Name	Property Type	Parameters
Biological Half-life	PHARMACOKINETIC
Tmax	PHARMACOKINETIC	ORAL ADMINISTRATION
Volume of Distribution	PHARMACOKINETIC