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Details

Stereochemistry ABSOLUTE
Molecular Formula C16H15N4O8S.Na
Molecular Weight 446.367
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CEFUROXIME SODIUM

SMILES

[Na+].[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C3=CC=CO3)C([O-])=O

InChI

InChIKey=URDOHUPGIOGTKV-JTBFTWTJSA-M
InChI=1S/C16H16N4O8S.Na/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20;/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24);/q;+1/p-1/b19-9-;/t10-,14-;/m1./s1

HIDE SMILES / InChI
Molecular Formula C16H15N4O8S
Molecular Weight 423.377
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 1
Optical Activity UNSPECIFIED
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:36:55 UTC 2023
Edited
by admin
on Fri Dec 15 15:36:55 UTC 2023
Record UNII
R8A7M9MY61
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CEFUROXIME SODIUM
EP   MART.   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD  
Common Name English
Cefuroxime sodium [WHO-DD]
Common Name English
CEFUROXIME SODIUM [USP-RS]
Common Name English
5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 3-(((AMINOCARBONYL)OXY)METHYL)-7-((2-FURANYL(METHOXYIMINO)ACETYL)AMINO)-8-OXO-, MONOSODIUM SALT (6R-(6.ALPHA.,7.BETA.(Z)))-
Common Name English
ZINACEF
Brand Name English
CEFUROXIME SODIUM [MART.]
Common Name English
KEFUROX
Brand Name English
CEFUROXIME SODIUM SALT [MI]
Common Name English
CEFUROXIME SODIUM [ORANGE BOOK]
Common Name English
CEFUROXIME SODIUM [USP MONOGRAPH]
Common Name English
CEFUROXIME SODIUM [EP IMPURITY]
Common Name English
CEFUROXIME SODIUM [JAN]
Common Name English
CEFUROXIME SODIUM SALT
MI  
Common Name English
CEFUROXIME SODIUM [EP MONOGRAPH]
Common Name English
CEFUROXIME SODIUM [USP IMPURITY]
Common Name English
CEFUROXIME SODIUM [VANDF]
Common Name English
SODIUM (6R,7R)-7-(2-(2-FURYL)GLYOXYLAMIDO)-3-(HYDROXYMETHYL)-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLATE, 7(SUP 2)-(Z)-(O-METHYLOXIME), CARBAMATE (ESTER)
Common Name English
SODIUM CEFUROXIME
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C357
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
Code System Code Type Description
FDA UNII
R8A7M9MY61
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
NCI_THESAURUS
C47439
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
RXCUI
204144
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY RxNorm
CAS
56238-63-2
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
DRUG BANK
DBSALT001160
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
EVMPD
SUB01140MIG
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
ChEMBL
CHEMBL1436
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
SMS_ID
100000091436
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
EPA CompTox
DTXSID201015616
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
ECHA (EC/EINECS)
260-073-1
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
MERCK INDEX
m3226
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY Merck Index
DAILYMED
R8A7M9MY61
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
PUBCHEM
23670318
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
RS_ITEM_NUM
1098209
Created by admin on Fri Dec 15 15:36:55 UTC 2023 , Edited by admin on Fri Dec 15 15:36:55 UTC 2023
PRIMARY
Related Record Type Details
Structure of CEFUROXIME
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of N-(2,2,2-TRICHLOROACETYL)CEFUROXIME
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of TRANS-CEFUROXIME
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DESCARBAMOYLCEFUROXIME
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (6R,7R)-7-(((Z)-(FURAN-2-YL)(METHOXYIMINO)ACETYL)AMINO)-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (6R,7R)-7-(((2E)-2-(2-FURANYL)-2-(METHOXYIMINO)ACETYL)AMINO)-3-(HYDROXYMETHYL)-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of METHOXYIMINOFURANYL ACETIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CEFURACETIME (E-ISOMER)
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CEFURACETIME
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DESCARBAMOYLCEFUROXIME LACTONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of CEFUROXIME
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