LAROTRECTINIB SULFATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H22F2N6O2.H2O4S
Molecular Weight	526.514
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.O[C@H]1CCN(C1)C(=O)NC2=C3N=C(C=CN3N=C2)N4CCC[C@@H]4C5=C(F)C=CC(F)=C5

InChI

InChIKey=PXHANKVTFWSDSG-QLOBERJESA-N

InChI=1S/C21H22F2N6O2.H2O4S/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27;1-5(2,3)4/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31);(H2,1,2,3,4)/t14-,18+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C21H22F2N6O2
Molecular Weight	428.4352
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:23:09 UTC 2023` Edited by `admin` on `Sat Dec 16 09:23:09 UTC 2023`
Record UNII	RDF76R62ID
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LAROTRECTINIB SULFATE

Official Name

English

VITRAKVI

Brand Name

English

LAROTRECTINIB SULFATE [USAN]

Common Name

English

1-PYRROLIDINECARBOXAMIDE, N-(5-((2R)-2-(2,5-DIFLUOROPHENYL)-1-PYRROLIDINYL)PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-3-HYDROXY-, (3S)-, SULFATE (1:1)

Systematic Name

English

Larotrectinib sulfate [WHO-DD]

Common Name

English

ARRY-470 SULFATE

Code

English

LAROTRECTINIB SULFATE [MI]

Common Name

English

(3S)-N-{5-[(2R)-2-(2,5-Difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl}-3-hydroxypyrrolidine-1-carboxamide sulfate (1:1)

Systematic Name

English

LOXO-101 SULFATE

Code

English

LAROTRECTINIB SULFATE [ORANGE BOOK]

Common Name

English

LAROTRECTINIB SULFATE [JAN]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/15/1606