LEUCOVORIN CALCIUM

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NCATS

Details

Stereochemistry	EPIMERIC
Molecular Formula	C20H21N7O7.Ca
Molecular Weight	511.501
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LEUCOVORIN CALCIUM

Structure Search

SMILES

[Ca++].NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)N2C=O)N1

InChI

InChIKey=KVUAALJSMIVURS-ZEDZUCNESA-L

InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C20H21N7O7
Molecular Weight	471.4234
Charge	-2
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	1 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	Ca
Molecular Weight	40.078
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 03:10:23 UTC 2023` Edited by `admin` on `Sat Dec 16 03:10:23 UTC 2023`
Record UNII	RPR1R4C0P4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LEUCOVORIN CALCIUM

Common Name

English

Calcium folinate [WHO-DD]

Common Name

English

FOLIC ACID RELATED COMPOUND A

Common Name

English

LEUCOVORIN CALCIUM [VANDF]

Common Name

English

NSC-3590

Code

English

CALCIUM FOLINATE [VANDF]

Common Name

English

FOLINIC ACID (AS CALCIUM FOLINATE)

Common Name

English

Folfox component leucovorin calcium

Common Name

English

CALCIUM N-(P-((((6RS)-2-AMINO-5-FORMYL-5,6,7,8-TETRAHYDRO-4-HYDROXY-6-PTERIDINYL)METHYL)AMINO)BENZOYL)-L-GLUTAMATE (1:1)

Common Name

English

L-GLUTAMIC ACID, N-(4-(((2-AMINO-5-FORMYL-1,4,5,6,7,8-HEXAHYDRO-4-OXO-6-PTERIDINYL)METHYL)AMINO)BENZOYL)-, CALCIUM SALT (1:1)

Common Name

English

CALCIUM FOLINATE [MART.]

Common Name

English

calcium folinate [INN]

Common Name

English

ANHYDROUS CALCIUM FOLINATE

Common Name

English

LEUCOVORIN CALCIUM [USP MONOGRAPH]

Common Name

English

CALCIUM FOLINATE [EP IMPURITY]

Common Name

English

LEUCOVORIN CALCIUM [USP-RS]

Common Name

English

LEUCOVORIN CALCIUM [ORANGE BOOK]

Common Name

English

CALCIUM FOLINATE

Official Name

English

FOLIC ACID RELATED COMPOUND A [USP-RS]

Common Name

English

CALCIUM FOLINATE [JAN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

V03AF03

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

WHO-VATC

QV03AF03

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

8.2

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

NCI_THESAURUS

C2078

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

FDA ORPHAN DRUG

29288

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

Code System Code Type Description

INN

690

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

NSC

3590

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

SMS_ID

100000090280

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

RS_ITEM_NUM

1286027

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

ALTERNATIVE

DAILYMED

RPR1R4C0P4

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

ChEMBL

CHEMBL1679

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

RS_ITEM_NUM

1358004

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

PUBCHEM

78759347

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

FDA UNII

RPR1R4C0P4

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

EVMPD

SUB21701

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

CAS

1492-18-8

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

EPA CompTox

DTXSID20872448

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

ECHA (EC/EINECS)

216-082-8

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

DRUG BANK

DB00650

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

RXCUI

225852

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

RxNorm

EVMPD

SUB06052MIG

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

NCI_THESAURUS

C607

Created by admin on Sat Dec 16 03:10:24 UTC 2023 , Edited by admin on Sat Dec 16 03:10:24 UTC 2023

PRIMARY

Related Record Type Details


					R3W57OBQ5W

LEUCOVORIN CALCIUM PENTAHYDRATE

SOLVATE->ANHYDROUS

Related Record Type Details


					AI902R79R1

10-FORMYLFOLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					5FW7ZL9BTK

5-FORMYLTETRAHYDROPTEROIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					C3XPF4ILH4

10-FORMYL-7,8-DIHYDROFOLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					935E97BOY8

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					9BKY99A8HJ

N-(P-AMINOBENZOYL)GLUTAMIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					VH29BN3FKN

5,10-DIFORMYLTETRAHYDROFOLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					KXP0KNM559

DIHYDROFOLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					Q573I9DVLP

ACTIVE MOIETY

Amount: