LIQUIRITIGENIN

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H12O4
Molecular Weight	256.2534
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LIQUIRITIGENIN

Structure Search

SMILES

OC1=CC=C(C=C1)[C@@H]2CC(=O)C3=CC=C(O)C=C3O2

InChI

InChIKey=FURUXTVZLHCCNA-AWEZNQCLSA-N

InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C15H12O4
Molecular Weight	256.2534
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:58:51 UTC 2023` Edited by `admin` on `Fri Dec 15 17:58:51 UTC 2023`
Record UNII	T194LKP9W6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LIQUIRITIGENIN

Official Name

English

4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-2-(4-HYDROXYPHENYL)-, (S)-

Systematic Name

English

FLAVANONE, 4',7-DIHYDROXY-

Systematic Name

English

LIQUIRITIGENIN [INCI]

Common Name

English

4',7-DIHYDROXYFLAVANONE

Systematic Name

English

(-)-LIQUIRITIGENIN

Common Name

English

(2S)-LIQUIRITIGENIN

Common Name

English

(-)-(2S)-7,4'-DIHYDROXYFLAVANONE

Systematic Name

English

7,4'-DIHYDROXYFLAVANONE

Systematic Name

English

4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-2-(4-HYDROXYPHENYL)-, (2S)-

Systematic Name

English

Code System Code Type Description

CHEBI

136678

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

CAS

578-86-9

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

EPA CompTox

DTXSID90206493

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

CHEBI

28777

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

FDA UNII

T194LKP9W6

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

PUBCHEM

114829

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

WIKIPEDIA

LIQUIRITIGENIN

Created by admin on Fri Dec 15 17:58:51 UTC 2023 , Edited by admin on Fri Dec 15 17:58:51 UTC 2023

PRIMARY

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LIQUIRITIGENIN was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.


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Comments:

Anti-HCV activity was found to be 16.4 ug/mL.

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