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Details

Stereochemistry RACEMIC
Molecular Formula C7H15Cl2N2O2P
Molecular Weight 261.086
Optical Activity ( + / - )
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IFOSFAMIDE

SMILES

ClCCNP1(=O)OCCCN1CCCl

InChI

InChIKey=HOMGKSMUEGBAAB-UHFFFAOYSA-N
InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)

HIDE SMILES / InChI
Molecular Formula C7H15Cl2N2O2P
Molecular Weight 261.086
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:57:02 UTC 2023
Edited
by admin
on Sat Dec 16 17:57:02 UTC 2023
Record UNII
UM20QQM95Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IFOSFAMIDE
EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
Z4942
Code English
2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE, N,3-BIS(2-CHLOROETHYL)TETRAHYDRO-, 2-OXIDE
Systematic Name English
NSC-109724
Code English
ISOCYCLOPHOSPHAMIDE
Common Name English
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
Systematic Name English
IFOSFAMIDE [USP-RS]
Common Name English
ifosfamide [INN]
Common Name English
IFOSFAMIDE [USAN]
Common Name English
IFOSFAMIDE [USP MONOGRAPH]
Common Name English
IFOSFAMIDE [EP IMPURITY]
Common Name English
MJF 9325
Code English
IFOSFAMIDE [MART.]
Common Name English
MJF-9325
Code English
IFOSFAMIDE [JAN]
Common Name English
Ifosfamide [WHO-DD]
Common Name English
Z-4942
Code English
IFOSFAMIDE [MI]
Common Name English
N,3-BIS(2-CHLOROETHYL)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE 2-OXIDE
Systematic Name English
IFOSFAMIDE [EP MONOGRAPH]
Common Name English
IFOSFAMIDE [HSDB]
Common Name English
ISOPHOSPHAMIDE [IARC]
Common Name English
IFOSFAMIDE [ORANGE BOOK]
Common Name English
IFOSFAMIDE [VANDF]
Common Name English
IFEX
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C697
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
WHO-VATC QL01AA06
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
WHO-ATC L01AA06
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
FDA ORPHAN DRUG 17786
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
NDF-RT N0000175558
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.2
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
NDF-RT N0000000236
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
LIVERTOX NBK548567
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
FDA ORPHAN DRUG 8585
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
Code System Code Type Description
PUBCHEM
3690
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
IUPHAR
7201
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
EVMPD
SUB08125MIG
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
DRUG BANK
DB01181
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
DRUG CENTRAL
1421
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
SMS_ID
100000083681
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
CAS
3778-73-2
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
FDA UNII
UM20QQM95Y
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
NCI_THESAURUS
C564
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
RS_ITEM_NUM
1336205
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
NSC
109724
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
CHEBI
5864
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
EPA CompTox
DTXSID7020760
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
INN
2865
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
WIKIPEDIA
IFOSFAMIDE
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
MERCK INDEX
m6207
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY Merck Index
RXCUI
5657
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY RxNorm
MESH
D007069
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
LACTMED
Ifosfamide
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
ECHA (EC/EINECS)
223-237-3
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
HSDB
7023
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
ChEMBL
CHEMBL1024
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
DAILYMED
UM20QQM95Y
Created by admin on Sat Dec 16 17:57:03 UTC 2023 , Edited by admin on Sat Dec 16 17:57:03 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 2B6
METABOLIC ENZYME -> SUBSTRATE
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Structure of 3-DECHLOROETHYLIFOSFAMIDE
METABOLITE INACTIVE -> PARENT
Found in erythrocytes too
PLASMA
Structure of 3-DECHLOROETHYLIFOSFAMIDE
METABOLITE INACTIVE -> PARENT
Structure of CARBOXYIFOSFAMIDE
METABOLITE -> PARENT
Found in erythrocytes
PLASMA
Structure of PALIFOSFAMIDE
METABOLITE ACTIVE -> PARENT
PLASMA
Structure of 2-DECHLOROETHYLIFOSFAMIDE
METABOLITE INACTIVE -> PARENT
Found in erythrocytes
PLASMA
Structure of 2,3-DIDECHLOROETHYL-IFOSFAMIDE
METABOLITE INACTIVE -> PARENT
Structure of 2-DECHLOROETHYLIFOSFAMIDE
METABOLITE INACTIVE -> PARENT
Structure of 4-KETOIFOSFAMIDE
METABOLITE -> PARENT
Found in erythrocytes too
PLASMA
Structure of ALDOIFOSFAMIDE
METABOLITE -> PARENT
In serum
Structure of ACROLEIN
METABOLITE TOXIC -> PARENT
MINOR
PLASMA
Structure of 2-CHLOROETHYLAMINE
METABOLITE -> PARENT
PLASMA
Structure of 4-HYDROXYIFOSFAMIDE
METABOLITE ACTIVE -> PRODRUG
labile intermediate
Related Record Type Details
Structure of MONOETHANOLAMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BIS(3-((2-CHLOROETHYL)AMINO)PROPYL) DIHYDROGEN DIPHOSPHATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-CHLORO-N-(2-CHLOROETHYL)PROPAN-1-AMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-((2-CHLOROETHYL)AMINO)PROPYL DIHYDROGEN PHOSPHATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-(CHLOROETHYL)-2-CHLOROOXAAZAPHOSPHORINANE 2-OXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-CHLOROETHYLAMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of 4-HYDROXYIFOSFAMIDE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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ACCESSIBILITY
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