FENITROTHION

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H12NO5PS
Molecular Weight	277.234
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENITROTHION

Structure Search

SMILES

COP(=S)(OC)OC1=CC(C)=C(C=C1)[N+]([O-])=O

InChI

InChIKey=ZNOLGFHPUIJIMJ-UHFFFAOYSA-N

InChI=1S/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3

HIDE SMILES / InChI

Molecular Formula	C9H12NO5PS
Molecular Weight	277.234
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:41:59 UTC 2023` Edited by `admin` on `Fri Dec 15 15:41:59 UTC 2023`
Record UNII	W8M4X3Y7ZY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FENITROTHION

Common Name

English

FENITROTHION [HSDB]

Common Name

English

FENITROTHION [ISO]

Common Name

English

FENITROTHION [MI]

Common Name

English

O,O-DIMETHYL O-4-NITRO-M-TOLYL PHOSPHOROTHIOATE

Systematic Name

English

O,O-DIMETHYL O-(3-METHYL-4-NITROPHENYL) PHOSPHOROTHIOATE

Systematic Name

English

FENITROTHION [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C471

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

EPA PESTICIDE CODE

105901

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

Code System Code Type Description

CHEBI

34757

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

HSDB

1590

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

ECHA (EC/EINECS)

204-524-2

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

PUBCHEM

31200

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

ALANWOOD

fenitrothion

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

CAS

122-14-5

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID4032613

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

WIKIPEDIA

FENITROTHION

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

MESH

D005278

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

MERCK INDEX

m5277

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

Merck Index

ChEMBL

CHEMBL347698

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

SMS_ID

300000023722

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

NCI_THESAURUS

C65655

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

FDA UNII

W8M4X3Y7ZY

Created by admin on Fri Dec 15 15:41:59 UTC 2023 , Edited by admin on Fri Dec 15 15:41:59 UTC 2023

PRIMARY

Related Record Type Details


					9DX651UO0D

CYTOCHROME P450 1A1

METABOLIC ENZYME -> INHIBITOR

Comments:

Fenitrothion inhibited CYP1A1/2 activities more than 90%

Amount:


					0UY97CSG1T

CYTOCHROME P450 2B6

METABOLIC ENZYME -> INHIBITOR

Comments:

Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Inhibition percentages were 100% with fenitrothion.


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> INHIBITOR

Comments:

CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides fenitrothion

Amount:


					VK4SQL11C0

CYTOCHROME P450 1A2

METABOLIC ENZYME -> INHIBITOR

Comments:

Fenitrothion inhibited CYP1A1/2 activities more than 90%.


					L0423Z5LDW

CYTOCHROME P450 2C8

METABOLIC ENZYME -> INHIBITOR

Comments:

inhibitions between 59 and 84% were observed with fenitrothion

Amount:


					246D9TQ2XG

CYTOCHROME P450 2A6

METABOLIC ENZYME -> INHIBITOR

Comments:

Extensive inhibitions of CYP2A6-associated activity (94–98%) were observed with fenitrothion,

Amount: