MOEXIPRIL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H34N2O7
Molecular Weight	498.5681
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=C(C[C@H]2C(O)=O)C=C(OC)C(OC)=C3

InChI

InChIKey=UWWDHYUMIORJTA-HSQYWUDLSA-N

InChI=1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H34N2O7
Molecular Weight	498.5681
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:46:27 UTC 2023` Edited by `admin` on `Fri Dec 15 15:46:27 UTC 2023`
Record UNII	WT87C52TJZ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MOEXIPRIL

Official Name

English

MOEXIPRIL [MI]

Common Name

English

3-ISOQUINOLINECARBOXYLIC ACID, 2-(2-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-, (3S-(2(R*(R*)),3R*))-

Common Name

English

moexipril [INN]

Common Name

English

(3S)-2-((2S)-N-((1S)-1-CARBOXY-3-PHENYLPROPYL)ALANYL)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-3-ISOQUINOLINECARBOXYLIC ACID, 2-ETHYL ESTER

Common Name

English

(3S)-2-((2S)-2-(((1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-3-ISOQUINOLINECARBOXYLIC ACID

Systematic Name

English

Moexipril [WHO-DD]

Common Name

English

MOEXIPRIL [VANDF]

Common Name

English

RS-10085

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C247

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

NDF-RT

N0000000181

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

LIVERTOX

NBK547904

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

WHO-ATC

C09AA13

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

WHO-VATC

QC09BA13

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

WHO-ATC

C09BA13

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

WHO-VATC

QC09AA13

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

NDF-RT

N0000175562

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

Code System Code Type Description

CAS

103775-10-6

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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LACTMED

Moexipril

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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INN

6266

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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EVMPD

SUB09030MIG

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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WIKIPEDIA

MOEXIPRIL

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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EPA CompTox

DTXSID9023330

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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SMS_ID

100000080331

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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PUBCHEM

91270

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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ChEMBL

CHEMBL1165

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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DRUG CENTRAL

1827

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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RXCUI

30131

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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RxNorm

MERCK INDEX

m7585

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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Merck Index

NCI_THESAURUS

C83967

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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FDA UNII

WT87C52TJZ

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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IUPHAR

6571

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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DRUG BANK

DB00691

Created by admin on Fri Dec 15 15:46:27 UTC 2023 , Edited by admin on Fri Dec 15 15:46:27 UTC 2023

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MESH

C058302

Created by admin on Fri Dec 15 15:46:28 UTC 2023 , Edited by admin on Fri Dec 15 15:46:28 UTC 2023

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Related Record Type Details


					Q1UMG3UH45

MOEXIPRIL HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					0A5Z1EG8ZG

ANGIOTENSIN-CONVERTING ENZYME 2

TARGET -> INHIBITOR


					U4GE85GV7N

MOEXIPRIL ETHYL ESTER

DERIVATIVE -> PARENT

Amount:


					51FM2R4Y24

ANGIOTENSIN-CONVERTING ENZYME

TARGET -> INHIBITOR

Related Record Type Details


					6SJ97G618S

PD-114009

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

PLASMA; URINE


					H3753190JS

MOEXIPRILAT

METABOLITE ACTIVE -> PRODRUG

Related Record Type Details


					H3753190JS

MOEXIPRILAT

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC