TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11

Approval Year

Substance Class	Protein
Protein Type	RECEPTOR
Protein Sub Type	Other
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZFQG2GI3F2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11

Common Name

English

PTPN11

Common Name

English

PROTEIN-TYROSINE PHOSPHATASE 1D

Common Name

English

SH-PTP3

Common Name

English

PROTEIN-TYROSINE PHOSPHATASE 2C

Common Name

English

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Code System

Code

Type

Description

CAS

301156-53-6

PRIMARY

FDA UNII

ZFQG2GI3F2

PRIMARY

UNIPROT

Q06124

PRIMARY

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Subunit 0

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Amount:


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Comments:

Greatly reduced effect in the SHP2 E76K or T253M/Q257L mutants.

Interaction Type:

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Qualification:

IC50

Amount:

0.53 NANOMOLAR (average)

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 68300 Da (average)

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