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Approval Year
Unknown
86,412
1921
1,382
2020
592
2012
529
2011
528
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Development Status
Other
73,727
Investigational
8,543
Possibly Marketed Outside US
3,724
Designated
153
Discontinued
116
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Primary Target
Dopamine D2 receptor
150
DNA
109
Serotonin 2a (5-HT2a) receptor
105
Dopamine transporter
102
Acetylcholinesterase
101
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Highest Phase
Approved
1,567
Phase II
854
Phase III
439
Phase I
353
Not Provided
310
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Condition
Unknown
1,512
Cancer
372
Pain
250
Breast cancer
227
Hypertension
202
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Treatment Modality
Primary
4,147
Curative
489
Palliative
362
Preventing
316
Diagnostic
205
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CNS Activity
CNS Active
1,705
CNS Penetrant
619
CNS Non-penetrant
209
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Originator
Pfizer
216
GlaxoSmithKline
125
Eli Lilly
107
Novartis
89
Merck
85
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Substance Class
Chemical
62,225
Structurally Diverse
14,664
Concept
4,823
Protein
2,131
Mixture
1,560
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INN Stem
Chemical substance(-ine)
178
Monoclonal antibodies(-mab)
17
Peptides and glycopeptides(-tide)
16
Prostaglandin analogue(-prost-)
9
Tyrosine-kinase inhibitors(-tinib)
8
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GInAS Tag
KEW
2,694
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Code System
FDA UNII
81,650
CAS
62,673
PUBCHEM
61,347
EPA CompTox
44,630
ECHA (EC/EINECS)
19,226
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Protein Type
MONOCLONAL ANTIBODY
268
RECEPTOR
109
ENZYME
92
MONOCLONAL ANTIBODY CONJUGATE
38
PEPTIDE
28
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ATC Level 1
NERVOUS SYSTEM
143
CARDIOVASCULAR SYSTEM
127
ALIMENTARY TRACT AND METABOLISM
115
ANTIINFECTIVES FOR SYSTEMIC USE
85
RESPIRATORY SYSTEM
78
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
63
PSYCHOLEPTICS
59
CARDIAC THERAPY
47
ANTINEOPLASTIC AGENTS
37
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
37
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ATC Level 3
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
30
HYPNOTICS AND SEDATIVES
25
ANTIPSYCHOTICS
23
DRUGS FOR FUNCTIONAL BOWEL DISORDERS
23
ANTIDEPRESSANTS
21
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ATC Level 4
Benzodiazepine derivatives
15
Antiinflammatory preparations, non-steroids for topical use
13
Other cough suppressants
12
Other psychostimulants and nootropics
12
Other vasodilators used in cardiac diseases
12
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Substance Form
Principal Form
72,772
Salts, Hydrates, Esters, etc.
8,878
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Approval Year
Unknown
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