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Development Status
Other
64,048
Possibly Marketed Outside US
8,632
Investigational
6,176
US Previously Marketed
1,279
US Approved Rx
1,241
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Primary Target
DNA
130
Dopamine D2 receptor
114
Apoptosis
111
GABA-A receptor; anion channel
102
Cyclooxygenase-2
97
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Highest Phase
Approved
2,732
Phase II
576
Phase III
318
Phase I
280
Not Provided
254
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Approval Year
Unknown
72,772
2020
512
1921
477
2012
465
2011
455
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Condition
Unknown
1,386
Cancer
346
Pain
243
Hypertension
205
Breast cancer
198
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Treatment Modality
Primary
4,095
Curative
647
Palliative
544
Preventing
472
Diagnostic
301
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CNS Activity
CNS Active
1,579
CNS Penetrant
865
CNS Non-penetrant
352
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Originator
Pfizer
177
GlaxoSmithKline
97
Merck
96
Eli Lilly
91
Novartis
84
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Substance Class
Chemical
57,842
Structurally Diverse
18,294
Protein
2,399
Mixture
2,116
Polymer
1,640
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INN Stem
Chemical substance(-ine)
226
Monoclonal antibodies(-mab)
18
Peptides and glycopeptides(-tide)
17
Tyrosine-kinase inhibitors(-tinib)
9
Chimeric antibody that responds to more than one antigen(-ximab)
4
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GInAS Tag
KEW
3,297
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Code System
FDA UNII
82,433
CAS
59,967
PUBCHEM
57,299
EPA CompTox
44,399
ECHA (EC/EINECS)
20,182
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Protein Type
MONOCLONAL ANTIBODY
340
RECEPTOR
109
ENZYME
104
MONOCLONAL ANTIBODY CONJUGATE
38
PEPTIDE
31
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ATC Level 1
NERVOUS SYSTEM
354
ALIMENTARY TRACT AND METABOLISM
296
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
255
CARDIOVASCULAR SYSTEM
254
ANTIINFECTIVES FOR SYSTEMIC USE
247
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ATC Level 2
ANTINEOPLASTIC AGENTS
157
ANTIBACTERIALS FOR SYSTEMIC USE
147
OPHTHALMOLOGICALS
139
PSYCHOLEPTICS
129
CARDIAC THERAPY
85
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
104
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
56
DIRECT ACTING ANTIVIRALS
55
HYPNOTICS AND SEDATIVES
52
ANTIPSYCHOTICS
51
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ATC Level 4
Protein kinase inhibitors
39
Other antineoplastic agents
36
Antibiotics
34
Benzodiazepine derivatives
29
Antidotes
26
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Substance Form
Principal Form
82,433
Salts, Hydrates, Esters, etc.
13,916
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Substance Form
Principal Form
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