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Development Status
US Approved Rx
930
Possibly Marketed Outside US
898
US Previously Marketed
456
US Approved OTC
115
Investigational
40
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Primary Target
Histamine H1 receptor
66
DNA
50
GABA-A receptor; anion channel
50
Dopamine D2 receptor
48
Bacterial penicillin-binding protein
43
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Highest Phase
Approved
1,744
Phase III
32
Not Provided
25
Phase II
21
Phase IV
6
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Approval Year
Unknown
808
1921
171
1996
38
1997
32
1959
31
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Condition
Unknown
102
Hypertension
99
Pain
75
Rheumatoid arthritis
50
Urinary tract infections
43
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Treatment Modality
Primary
1,256
Curative
368
Palliative
334
Preventing
205
Diagnostic
119
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CNS Activity
CNS Active
507
CNS Penetrant
434
CNS Non-penetrant
200
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Originator
Pfizer
41
Merck
32
Hoffman-La Roche
29
Bayer
23
Boehringer Ingelheim
23
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Substance Class
Chemical
2,202
Protein
131
Mixture
78
Polymer
29
Structurally Diverse
25
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INN Stem
Chemical substance(-ine)
1
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Code System
WHO-VATC
2,476
FDA UNII
2,468
CAS
2,443
EVMPD
2,356
NCI_THESAURUS
2,312
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Protein Type
MONOCLONAL ANTIBODY
21
CYTOKINE
4
ENZYME
4
GROWTH FACTOR
3
HORMONE
3
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ATC Level 1
NERVOUS SYSTEM
378
ALIMENTARY TRACT AND METABOLISM
352
CARDIOVASCULAR SYSTEM
287
ANTIINFECTIVES FOR SYSTEMIC USE
220
DERMATOLOGICALS
210
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ATC Level 2
OPHTHALMOLOGICALS
153
ANTIBACTERIALS FOR SYSTEMIC USE
151
PSYCHOLEPTICS
126
ANTINEOPLASTIC AGENTS
119
CARDIAC THERAPY
94
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
62
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
60
ANTIINFECTIVES
55
HYPNOTICS AND SEDATIVES
52
ALL OTHER THERAPEUTIC PRODUCTS
51
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ATC Level 4
Antibiotics
36
Antidotes
30
Benzodiazepine derivatives
29
Other antineoplastic agents
25
Antiinflammatory preparations, non-steroids for topical use
23
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Substance Form
Principal Form
2,028
Salts, Hydrates, Esters, etc.
440
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