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Development Status
Investigational
69
Possibly Marketed Outside US
66
US Approved Rx
33
US Previously Marketed
33
Other
2
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Primary Target
Plasmodium falciparum
12
Ferriprotoporphyrin IX
11
DNA
9
UniProtKB: D6BK80_HAECO | D6BJF3_HAECO (GABA receptor subunit)
5
L-lactate dehydrogenase
4
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Highest Phase
Approved
102
Not Provided
5
Phase II
4
Phase III
4
Phase IV
1
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Approval Year
Unknown
115
1921
13
1950
8
1943
4
1955
4
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Condition
Malaria
16
Coccidiosis
12
Helminthiasis
12
Plasmodium falciparum malaria
11
Trichomoniasis
6
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Treatment Modality
Curative
100
Primary
26
Preventing
15
Palliative
4
Secondary
1
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CNS Activity
CNS Penetrant
27
CNS Active
16
CNS Non-penetrant
8
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Originator
Pfizer
9
Merck
7
Bayer
5
Rhône-Poulenc
4
Imperial Chemical Industries
3
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Substance Class
Chemical
202
Mixture
4
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Code System
FDA UNII
206
NCI_THESAURUS
206
CAS
205
PUBCHEM
200
EPA CompTox
196
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ATC Level 1
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
41
DERMATOLOGICALS
4
GENITO URINARY SYSTEM AND SEX HORMONES
3
ALIMENTARY TRACT AND METABOLISM
2
ANTIINFECTIVES FOR SYSTEMIC USE
1
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ATC Level 2
ANTIPROTOZOALS
27
ANTHELMINTICS
14
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
3
ANTIBACTERIALS FOR SYSTEMIC USE
1
ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
1
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ATC Level 3
ANTIMALARIALS
12
AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
10
ANTINEMATODAL AGENTS
7
AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
5
ANTITREMATODALS
4
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ATC Level 4
Artemisinin and derivatives, combinations
6
Other agents against amoebiasis and other protozoal diseases
5
Benzimidazole derivatives
4
Nitroimidazole derivatives
4
Aminoquinolines
3
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Substance Form
Principal Form
136
Salts, Hydrates, Esters, etc.
70
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Search results for
"Pharmacologic Substance[C1909]|Anti-Infective Agent[C254]|Antiparasitic Agent[C276]"
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BRINDOXIME
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5CA81DKM2L
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Other
Class (Stereo):
CHEMICAL (RACEMIC)
UREDOFOS
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P8W25X9B3K
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CHEMICAL (ACHIRAL)
BITIPAZONE
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4HM3435J27
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CHEMICAL (ACHIRAL)
CLOCIGUANIL
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32W4ZSE0X7
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CHEMICAL (ACHIRAL)
NICLOFOLAN
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82KFT81F6W
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CHEMICAL (ACHIRAL)
PEXANTEL
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HOH9HJ2737
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CHEMICAL (ACHIRAL)
ETIBENDAZOLE
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1XU086MM3H
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CHEMICAL (ACHIRAL)
FORMINITRAZOLE
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GTW8DB3OVN
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CHEMICAL (ACHIRAL)
PIRINIDAZOLE
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YL02E256HT
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Class (Stereo):
CHEMICAL (ACHIRAL)
AMINOQUINOL
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CH1Y88E2AY
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Class (Stereo):
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