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Development Status
Possibly Marketed Outside US
131
US Approved Rx
118
US Previously Marketed
53
US Approved OTC
7
Other
3
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Primary Target
Beta-1 adrenergic receptor
22
Angiotensin-converting enzyme
16
Beta-2 adrenergic receptor
14
Thiazide-sensitive sodium-chloride cotransporter
11
Voltage-gated L-type calcium channel
11
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Highest Phase
Approved
228
Phase III
7
Phase II
5
Not Provided
3
Phase IV
2
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Approval Year
Unknown
127
1921
19
1954
7
1997
7
1987
5
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Condition
Hypertension
95
Heart failure
24
Angina pectoris
19
Myocardial infarction
19
Angina
11
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Treatment Modality
Primary
230
Palliative
43
Preventing
20
Curative
7
Diagnostic
7
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CNS Activity
CNS Penetrant
65
CNS Active
58
CNS Non-penetrant
30
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Originator
Junkmann, K.
8
Pfizer
8
Bayer
5
Ciba-Geigy
5
Merck
5
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Substance Class
Chemical
292
Protein
6
Mixture
4
Polymer
4
Concept
3
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Code System
WHO-ATC
313
FDA UNII
310
CAS
308
EVMPD
304
EPA CompTox
298
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Protein Type
MONOCLONAL ANTIBODY
2
PEPTIDE
1
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ATC Level 1
CARDIOVASCULAR SYSTEM
313
SENSORY ORGANS
22
RESPIRATORY SYSTEM
14
DERMATOLOGICALS
13
ALIMENTARY TRACT AND METABOLISM
10
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ATC Level 2
CARDIAC THERAPY
100
LIPID MODIFYING AGENTS
38
ANTIHYPERTENSIVES
37
DIURETICS
35
AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
34
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ATC Level 3
LIPID MODIFYING AGENTS, PLAIN
31
CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
26
ANTIARRHYTHMICS, CLASS I AND III
23
PERIPHERAL VASODILATORS
23
VASODILATORS USED IN CARDIAC DISEASES
23
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ATC Level 4
Adrenergic and dopaminergic agents
20
Other vasodilators used in cardiac diseases
16
ACE inhibitors, plain
15
Other cardiac preparations
15
Beta blocking agents, selective
12
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Substance Form
Principal Form
254
Salts, Hydrates, Esters, etc.
56
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Search results for
"ATC|CARDIOVASCULAR SYSTEM"
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NICARDIPINE
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CZ5312222S
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Other
Class (Stereo):
CHEMICAL (RACEMIC)
AMLODIPINE
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1J444QC288
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CHEMICAL (RACEMIC)
MILRINONE
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JU9YAX04C7
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CHEMICAL (ACHIRAL)
LISINOPRIL ANHYDROUS
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7Q3P4BS2FD
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CHEMICAL (ABSOLUTE)
ESMOLOL
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MDY902UXSR
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CHEMICAL (RACEMIC)
GUANFACINE
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30OMY4G3MK
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Class (Stereo):
CHEMICAL (ACHIRAL)
MEXILETINE
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1U511HHV4Z
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Class (Stereo):
CHEMICAL (RACEMIC)
BETAXOLOL
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O0ZR1R6RZ2
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Class (Stereo):
CHEMICAL (RACEMIC)
AMIODARONE
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N3RQ532IUT
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Class (Stereo):
CHEMICAL (ACHIRAL)
ACEBUTOLOL
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67P356D8GH
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Class (Stereo):
CHEMICAL (RACEMIC)
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