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Development Status
Investigational
33
US Approved Rx
32
US Previously Marketed
17
Possibly Marketed Outside US
16
US Approved OTC
8
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Primary Target
Dopamine D2 receptor
21
Histamine H1 receptor
16
Serotonin 3a (5-HT3a) receptor
13
Muscarinic acetylcholine receptor M1
8
Dopamine D1 receptor
7
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Highest Phase
Approved
64
Not Provided
2
Phase II
1
Phase III
1
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Approval Year
Unknown
48
1959
6
1954
5
1956
5
1951
4
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Condition
Postoperative nausea and vomiting
13
Nausea
11
Schizophrenia
11
Vomiting
11
Motion sickness
9
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Treatment Modality
Primary
43
Preventing
15
Secondary
13
Palliative
10
Curative
1
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CNS Activity
CNS Active
40
CNS Penetrant
18
CNS Non-penetrant
2
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Originator
Rhône-Poulenc
5
Charpentier, P. at Rhône-Poulenc
4
GlaxoSmithKline
4
Delagrange
3
Pfizer
3
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Substance Class
Chemical
106
Concept
1
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INN Stem
Chemical substance(-ine)
1
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Code System
CAS
107
NCI_THESAURUS
107
FDA UNII
106
ChEMBL
101
SMS_ID
101
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ATC Level 1
ALIMENTARY TRACT AND METABOLISM
13
NERVOUS SYSTEM
10
RESPIRATORY SYSTEM
5
DERMATOLOGICALS
4
CARDIOVASCULAR SYSTEM
1
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ATC Level 2
ANTIEMETICS AND ANTINAUSEANTS
9
PSYCHOLEPTICS
9
ANTIHISTAMINES FOR SYSTEMIC USE
4
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
3
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
3
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ATC Level 3
ANTIEMETICS AND ANTINAUSEANTS
9
ANTIPSYCHOTICS
8
ANTIHISTAMINES FOR SYSTEMIC USE
4
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
3
PROPULSIVES
3
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ATC Level 4
Other antiemetics
5
Phenothiazines with aliphatic side-chain
4
Serotonin (5HT3) antagonists
4
Antihistamines for topical use
3
Phenothiazines with piperazine structure
3
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Substance Form
Principal Form
65
Salts, Hydrates, Esters, etc.
41
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Search results for
"Pharmacologic Substance[C1909]|Agent Affecting Nervous System[C78272]|Antiemetic Agent"
in
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CIPROPRIDE
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0D2VUO6DCN
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Status:
Other
Class (Stereo):
CHEMICAL (UNKNOWN)
BATANOPRIDE
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1AT99K728N
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Class (Stereo):
CHEMICAL (RACEMIC)
FIGOPITANT
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23X73B9O6Q
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CHEMICAL (ABSOLUTE)
FLUMERIDONE
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7ZZN46QU1N
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Class (Stereo):
CHEMICAL (ACHIRAL)
VESTIPITANT
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S052TOI9BI
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Class (Stereo):
CHEMICAL (ABSOLUTE)
MOCIPRAZINE
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L3L0CM26R6
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Class (Stereo):
CHEMICAL (RACEMIC)
TINISULPRIDE
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037S03TJ5M
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Class (Stereo):
CHEMICAL (RACEMIC)
LANEPITANT
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17G8FN2E1F
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Class (Stereo):
CHEMICAL (ABSOLUTE)
LEVONANTRADOL
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03S640ADSK
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Class (Stereo):
CHEMICAL (ABSOLUTE)
LINTOPRIDE
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C2R0GEU722
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Class (Stereo):
CHEMICAL (ACHIRAL)
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