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Development Status
Investigational
30
Possibly Marketed Outside US
8
US Approved Rx
7
Designated
4
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Primary Target
DNA
3
Tyrosine-protein kinase receptor FLT3
3
DNA topoisomerase II
2
Multidrug resistance-associated protein 1
2
Serine/threonine-protein kinase Aurora-A
2
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Highest Phase
Phase II
9
Phase III
9
Approved
6
Phase I
2
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Approval Year
Unknown
41
2023
3
1978
1
1979
1
2004
1
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Condition
Acute myeloid leukemia
11
Myelodysplastic syndromes
5
Ovarian cancer
4
Acute lymphoblastic leukemia
3
Breast cancer
3
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Treatment Modality
Primary
26
Palliative
1
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CNS Activity
CNS Penetrant
5
CNS Active
2
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Originator
Ambit Biosciences
1
Astex Therapeutics
1
Bykov, V.J. et al.
1
CGI Pharmaceuticals
1
Clavis Pharma
1
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Substance Class
Chemical
45
Protein
3
Mixture
1
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INN Stem
Peptides and glycopeptides(-tide)
1
Tyrosine-kinase inhibitors(-tinib)
1
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Code System
FDA ORPHAN DRUG
49
FDA UNII
49
CAS
46
NCI_THESAURUS
44
PUBCHEM
42
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Protein Type
MONOCLONAL ANTIBODY
2
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
4
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
1
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ATC Level 2
ANTINEOPLASTIC AGENTS
4
ANTIPROTOZOALS
1
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
3
AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
1
ANTIMETABOLITES
1
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ATC Level 4
Other antineoplastic agents
3
Antimony compounds
1
Purine analogues
1
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Substance Form
Principal Form
33
Salts, Hydrates, Esters, etc.
16
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Search results for
"ORPHAN DRUG|Designated|Treatment of Acute myeloid leukemia"
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ELACYTARABINE
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TA7WJG93AR
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Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
ZOSUQUIDAR TRIHYDROCHLORIDE
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813AGY3126
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TRICIRIBINE PHOSPHATE
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5L5GE3DV88
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CHEMICAL (ABSOLUTE)
BARASERTIB TRIHYDRATE
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WM1NC31680
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CHEMICAL (ACHIRAL)
SEL-24 HYDROCHLORIDE
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1Z0H0278DB
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CHEMICAL (ACHIRAL)
TETRANDRINE, (+)-
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29EX23D5AJ
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CHEMICAL (ABSOLUTE)
CRIDANIMOD SODIUM
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54W868ROLR
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Class (Stereo):
CHEMICAL (ACHIRAL)
SODIUM STIBOGLUCONATE ANHYDROUS
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V083S0159D
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Class (Stereo):
CHEMICAL (ABSOLUTE)
BISANTRENE HYDROCHLORIDE
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74GNV897RO
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Class (Stereo):
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