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Development Status
Investigational
256
Possibly Marketed Outside US
130
US Approved Rx
66
US Previously Marketed
33
US Approved OTC
13
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Primary Target
Cyclooxygenase-2
67
Cyclooxygenase-1
52
Cyclooxygenase
37
Prostaglandin G/H synthase 2
15
Mu opioid receptor
13
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Highest Phase
Approved
162
Phase II
17
Not Provided
15
Phase III
13
Phase I
5
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Approval Year
Unknown
378
1860
9
1988
9
1976
8
1921
6
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Condition
Rheumatoid arthritis
68
Osteoarthritis
60
Pain
57
Arthritis
18
Ankylosing spondylitis
13
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Treatment Modality
Primary
177
Palliative
96
Preventing
12
Curative
4
Secondary
3
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CNS Activity
CNS Active
67
CNS Penetrant
42
CNS Non-penetrant
18
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Originator
Pfizer
11
Cahours, A.A.T.
9
Merck
9
Hoffman-La Roche
7
Ciba-Geigy
6
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Substance Class
Chemical
500
Protein
6
Mixture
2
Concept
1
Structurally Diverse
1
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Code System
NCI_THESAURUS
510
FDA UNII
509
CAS
507
PUBCHEM
498
ChEMBL
464
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Protein Type
HORMONE
1
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ATC Level 1
MUSCULO-SKELETAL SYSTEM
58
NERVOUS SYSTEM
35
SENSORY ORGANS
13
GENITO URINARY SYSTEM AND SEX HORMONES
6
RESPIRATORY SYSTEM
4
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ATC Level 2
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
49
ANALGESICS
29
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
27
OPHTHALMOLOGICALS
12
OTHER GYNECOLOGICALS
4
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ATC Level 3
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
48
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
27
OTHER ANALGESICS AND ANTIPYRETICS
21
ANTIINFLAMMATORY AGENTS
11
OPIOIDS
7
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ATC Level 4
Antiinflammatory preparations, non-steroids for topical use
25
Propionic acid derivatives
15
Acetic acid derivatives and related substances
12
Salicylic acid and derivatives
12
Antiinflammatory agents, non-steroids
11
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Substance Form
Principal Form
396
Salts, Hydrates, Esters, etc.
113
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Search results for
"Pharmacologic Substance[C1909]|Agent Affecting Nervous System[C78272]|Analgesic Agent"
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